ribosome

noun

ri·​bo·​some ˈrī-bə-ˌsōm How to pronounce ribosome (audio)
: any of the RNA-rich cytoplasmic granules that are sites of protein synthesis see cell illustration
ribosomal adjective

Examples of ribosome in a Sentence

Recent Examples on the Web
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In one case, while redesigning a ribosomal protein called RpsJ, the AI remodeled an alpha helix—a structural element bridging different parts of the ribosome—and introduced eight new nearby mutations to compensate for the substitution of just two isoleucines. Jacek Krywko, Scientific American, 30 Apr. 2026 To do that, the researchers decided to remove isoleucine from all of the proteins in the small subunit of the ribosome. ArsTechnica, 30 Apr. 2026 Further experiments suggested that cells can use ribosomes — one of the most abundant molecules in a cell — and the genetic pathways that regulate them, to control their molecular crowds. Quanta Magazine, 18 Feb. 2026 Then there's ribosomal RNA (rRNA) that creates ribosomes vital for producing proteins, and finally transfer RNA (tRNA) that does the actual synthesizing of the proteins from mRNA. Keith Cooper, Space.com, 5 Jan. 2026 See All Example Sentences for ribosome

Word History

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ribosome was in 1958

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Cite this Entry

“Ribosome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ribosome. Accessed 7 May. 2026.

Kids Definition

ribosome

noun
ri·​bo·​some ˈrī-bə-ˌsōm How to pronounce ribosome (audio)
: one of numerous small RNA-containing particles in a cell that are sites of protein synthesis

Medical Definition

ribosome

noun
ri·​bo·​some ˈrī-bə-ˌsōm How to pronounce ribosome (audio)
: any of the RNA- and protein-rich cytoplasmic granules that are sites of protein synthesis
ribosomal adjective

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