reverse transcription

noun

: the process of synthesizing DNA using RNA as a template and reverse transcriptase as a catalyst

Example Sentences

Recent Examples on the Web

Then comes the critical step: a reverse transcription polymerase chain reaction, or RT-PCR, which exponentially copies target RNA sequences to detectable levels. —Christian Elliott, Discover Magazine, 4 Feb. 2022

To sequence the genetic material, the Pandemic Response Lab first converts the RNA into DNA, a process known as reverse transcription. —New York Times, 17 Aug. 2022

Following reverse transcription–polymerase chain reaction (RT-PCR) testing and genomic sequencing of the samples, each family member was found to be infected by the Omicron variant of COVID-19. —Ashley Abramson, Health.com, 29 Dec. 2021

The data presented by Moderna Thursday limited the analysis only to cases confirmed positive by sensitive reverse transcription-polymerase chain reaction tests. —Brenda Goodman, CNN, 28 Apr. 2022

But experts say the PCR test isn't the best one for every situation. PCR -- or reverse transcription-polymerase chain reaction -- tests can detect small amounts of the coronavirus' genetic material in a specimen collected from a human. —Kristen Rogers, CNN, 19 Jan. 2022

The Bubbler is a glass tube filled with a reverse transcription reaction mixture and a cold mineral oil. —Globe Staff, BostonGlobe.com, 16 Dec. 2021

Those tests are known as: reverse transcription polymerase chain reaction (RT-PCR) tests, viral cultures, or immunofluorescence assays, the CDC says. —Ashley Abramson, Health.com, 14 Oct. 2021

Scientists distinguish variants using a process called quantitative reverse transcription polymerase chain reaction. —Marlene Lenthang, ABC News, 23 June 2021

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Word History

First Known Use

1971, in the meaning defined above

Medical Definition

reverse transcription

noun

: the process of synthesizing DNA using RNA as a template and reverse transcriptase as a catalyst

reverse-transcribe transitive verb

reverse transcribed; reverse transcribing