reuptake

noun

re·​up·​take (ˈ)rē-ˈəp-ˌtāk How to pronounce reuptake (audio)
: the reabsorption by a neuron of a neurotransmitter following the transmission of a nerve impulse across a synapse

Examples of reuptake in a Sentence

Recent Examples on the Web Two categories of drugs — antidepressants known as SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotonin-norepinephrine reuptake inhibitors) — are typically prescribed, and both appear to help to older adults, experts said. Judith Graham, CNN, 6 Mar. 2023 Within this category are selective serotonin reuptake inhibitors (SSRIs), like Lexapro and Zoloft, or serotonin and norepinephrine reuptake inhibitors (SNRIs), like Pristiq and Cymbalta, per Mayo Clinic. Sarah Fielding, Health.com, 6 Dec. 2021 Serotonin and norepinephrine reuptake inhibitors (SNRIs) are also considered an option during pregnancy, Sophocles added. Madeline Holcombe, CNN, 15 May 2023 Another drug Clancy was prescribed called trazodone (often used in small doses for insomnia), shares many properties with SSRIs but is in a separate class of drugs called serotonin receptor antagonists and reuptake inhibitors, or SARIs. Jessica Bartlett, BostonGlobe.com, 3 Feb. 2023 These drugs increase the levels of dopamine and norepinephrine in the brain by blocking their reuptake. Avery Hurt, Discover Magazine, 22 Mar. 2023 Since lower levels of serotonin are linked to sadness and depression, it is thought that by preventing the reuptake of serotonin, SSRIs fake higher overall serotonin levels and thus boost happy feelings. Christie Wilcox, Discover Magazine, 6 Oct. 2011 Serotonin-noradrenaline reuptake inhibitors Like SSRIs, SNRIs target serotonin receptors but these medications also target noradrenaline, another neurotransmitter believed to be deficient in those with depression. Jodi Helmer, Fortune Well, 26 Mar. 2023 Two categories of drugs — antidepressants known as SSRIs (selective serotonin reuptake inhibitors) and SNRIs (serotonin-norepinephrine reuptake inhibitors) — are typically prescribed, and both appear to help to older adults, experts said. Judith Graham, CNN, 6 Mar. 2023

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'reuptake.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1968, in the meaning defined above

Time Traveler
The first known use of reuptake was in 1968

Dictionary Entries Near reuptake

Cite this Entry

“Reuptake.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/reuptake. Accessed 22 Jun. 2024.

Medical Definition

reuptake

noun
re·​up·​take (ˈ)rē-ˈəp-ˌtāk How to pronounce reuptake (audio)
: the reabsorption by a neuron of a neurotransmitter following the transmission of a nerve impulse across a synapse
antidepressants which block the reuptake of norepinephrine
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