re·​up·​take | \ (ˈ)rē-ˈəp-ˌtāk How to pronounce reuptake (audio) \

Definition of reuptake

: the reabsorption by a neuron of a neurotransmitter following the transmission of a nerve impulse across a synapse

Examples of reuptake in a Sentence

Recent Examples on the Web

These days, about 5 percent of expectant mothers use antidepressants, most commonly, serotonin reuptake inhibitors, or SSRIs, such as citalopram (brand name Celexa), paroxetine (Paxil), or sertraline (Zoloft). Julia Belluz, Vox, "We’re beginning to learn how moms’ antidepressants can affect fetuses," 9 Apr. 2018 And then, in the late 1980s there’s the arrival of serotonin reuptake inhibitors, known as SSRIs, and their promise to be different from the antidepressants of the past. Maggie Jones, New York Times, "A Reckoning With an Imperfect Science in ‘Blue Dreams’," 3 Apr. 2018 SSRIs work by blocking the reabsorption (reuptake) of serotonin in the brain, according to the Mayo Clinic. Martine Thompson, SELF, "8 Things You Should Know Before Going on Antidepressants for the First Time," 30 Mar. 2018 These also work to prevent the reuptake of GABA by neurons, prolonging the effect. Christie Wilcox, Scientific American, "How a Wasp Turns Cockroaches into Zombies," 1 May 2017 Some benefit was found for another type of antidepressant — serotonin and norepinephrine reuptake inhibitors or SNRIs — but the researchers described the results as inconsistent. Linda Searing, Washington Post, "For excessively anxious youths, the success of treatment options varies," 4 Sep. 2017 The antidepressant Prozac, a selective-serotonin reuptake inhibitor (or SSRI), is one of the world's most widely used medications. Los Angeles Times,, "Could Prozac be a treatment for children with autism?," 22 June 2017 Traditional selective serotonin reuptake inhibitors like Prozac can do the same thing, but that process could take months. Rene Chun, Los Angeles Magazine, "Inside the Los Angeles Clinic That Uses Ketamine to Treat Depression," 19 June 2017 Focusing on selective serotonin reuptake inhibitors — Brandon Keim, WIRED, "For Newborns, Mom’s Antidepressants Less Risky Than Mom’s Depression," 28 June 2007

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'reuptake.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of reuptake

1968, in the meaning defined above

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The first known use of reuptake was in 1968

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re·​up·​take | \ (ˈ)rē-ˈəp-ˌtāk How to pronounce reuptake (audio) \

Medical Definition of reuptake

: the reabsorption by a neuron of a neurotransmitter following the transmission of a nerve impulse across a synapse antidepressants which block the reuptake of norepinephrine

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to spread over or through

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