reuptake

noun

re·​up·​take (ˈ)rē-ˈəp-ˌtāk How to pronounce reuptake (audio)
: the reabsorption by a neuron of a neurotransmitter following the transmission of a nerve impulse across a synapse

Examples of reuptake in a Sentence

Recent Examples on the Web
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As the Mayo Clinic explains, Duloxetine is a type of selective serotonin and norepinephrine reuptake inhibitor (SSNRIs) which works by increasing serotonin and norepinephrine in the brain. Cara Lynn Shultz, PEOPLE, 15 June 2026 Much of the conversation around potential risks has centered on selective-serotonin reuptake inhibitors, which are known as SSRIs and are the most prescribed class of antidepressants. Kristen Rogers, CNN Money, 14 May 2026 Other medication classes, such as serotonin-norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants or tricyclic antidepressants, may also be used depending on individual needs. Daryl Austin, USA Today, 14 Mar. 2026 Specifically, Isaacson wonders about the long-term effects of her medication, a serotonin-norepinephrine reuptake inhibitor that is known to raise blood pressure. The New York Times News Service Syndicate, San Diego Union-Tribune, 27 Jan. 2026 See All Example Sentences for reuptake

Word History

First Known Use

1968, in the meaning defined above

Time Traveler
The first known use of reuptake was in 1968

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Cite this Entry

“Reuptake.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/reuptake. Accessed 24 Jun. 2026.

Medical Definition

reuptake

noun
re·​up·​take (ˈ)rē-ˈəp-ˌtāk How to pronounce reuptake (audio)
: the reabsorption by a neuron of a neurotransmitter following the transmission of a nerve impulse across a synapse
antidepressants which block the reuptake of norepinephrine
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