rep·​li·​ca·​tion | \ ˌre-plə-ˈkā-shən How to pronounce replication (audio) \

Definition of replication

1a : answer, reply
b(1) : an answer to a reply : rejoinder
(2) : a plaintiff's reply to a defendant's plea, answer, or counterclaim
b : the action or process of reproducing or duplicating replication of DNA viral replication
4 : performance of an experiment or procedure more than once

Keep scrolling for more

Examples of replication in a Sentence

bought a smaller and cheaper replication of the marble statue for his garden we'll need to do a replication of that experiment so we can collect more data
Recent Examples on the Web Less replication means less opportunity for the virus to mutate and become potentially dangerous variants. Holly Yan, CNN, "It's possible to reach herd immunity, then lose it. Repeatedly. Here's what you can do to help prevent that from happening," 30 Mar. 2021 Every generation of viral replication inside humans rolls a set of unpredictable genetic dice very capable of landing everyone in a tougher spot. Paul Sisson, San Diego Union-Tribune, "Experts demand discipline as COVID-19 eases: ‘We don’t want to have to start over’," 28 Mar. 2021 Islatravir, which Merck licensed from Japan’s Yamasa Corp. in 2012, stops the virus from copying its genetic material and disrupts a later stage in its replication process. Jonathan D. Rockoff, WSJ, "Gilead and Merck Join Forces to Develop Long-Acting HIV Treatment," 15 Mar. 2021 Increasing the rate of cleavage may benefit the virus in two ways: increasing its ability to be transmitted and increasing the efficiency of replication once the infection has been initiated. William A. Haseltine, Forbes, "Identification Of A Novel Covid-19 Variant Cluster Isolated From Covid-19 Ill Infants In US Capital," 25 Feb. 2021 Mutations are the result of small copying errors that occur during the virus replication process. Emily Woodruff,, "As coronavirus variant gains ground in Louisiana, officials predict 'another spike in our future'," 2 Feb. 2021 In an August 2020 preprint on bioRxiv, Weetall and colleagues reported that PTC299 sharply inhibited SARS-CoV-2 replication in cells. Robert F. Service, Science | AAAS, "Researchers race to develop antiviral weapons to fight the pandemic coronavirus," 11 Mar. 2021 This strategy must be supplemented by solutions that support effective backup, replication and recovery to maintain full access to information at any time, from anywhere, to drive business operations forward. Expert Panel®, Forbes, "Moving To The Cloud? 13 Steps To Optimize Savings And Efficiency," 3 Mar. 2021 Luckily, the mutation rate of coronaviruses generally is relatively slow, due to a proofreading ability in the virus that allows for some correction of replication mistakes. Quanta Magazine, "How to Understand COVID-19 Variants and Their Effects on Vaccines," 25 Feb. 2021

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'replication.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

See More

First Known Use of replication

14th century, in the meaning defined at sense 1a

Keep scrolling for more

Learn More about replication

Time Traveler for replication

Time Traveler

The first known use of replication was in the 14th century

See more words from the same century

Statistics for replication

Last Updated

9 Apr 2021

Cite this Entry

“Replication.” Dictionary, Merriam-Webster, Accessed 19 Apr. 2021.

Style: MLA
MLACheck Mark Icon ChicagoCheck Mark Icon APACheck Mark Icon Merriam-WebsterCheck Mark Icon

Keep scrolling for more

More Definitions for replication


rep·​li·​ca·​tion | \ ˌrep-lə-ˈkā-shən How to pronounce replication (audio) \

Medical Definition of replication

1 : the action or process of reproducing or duplicating replication of DNA
2 : performance of an experiment or procedure more than once


rep·​li·​ca·​tion | \ ˌre-plə-ˈkā-shən How to pronounce replication (audio) \

Legal Definition of replication

: reply

History and Etymology for replication

Anglo-French, from Middle French, from Late Latin replicatio, from Latin, action of folding back, from replicare to fold back

Keep scrolling for more

Comments on replication

What made you want to look up replication? Please tell us where you read or heard it (including the quote, if possible).


Test Your Vocabulary

Name that Thing: Flower Edition

True or False

Test your knowledge - and maybe learn something along the way.

Universal Daily Crossword

A daily challenge for crossword fanatics.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!