rep·​li·​ca·​tion | \ ˌre-plə-ˈkā-shən How to pronounce replication (audio) \

Definition of replication

b(1) : an answer to a reply : rejoinder
(2) : a plaintiff's reply to a defendant's plea, answer, or counterclaim
b : the action or process of reproducing or duplicating replication of DNA viral replication
4 : performance of an experiment or procedure more than once

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Examples of replication in a Sentence

bought a smaller and cheaper replication of the marble statue for his garden we'll need to do a replication of that experiment so we can collect more data
Recent Examples on the Web The dismantling of the Tin Building and its replication on a new site has been a rare and extreme intervention for a structure within a historic district. John Freeman Gill, New York Times, "A Slice of the Fulton Fish Market Gets A New Life," 28 Feb. 2020 One drug in place for the Congo outbreak was remdesivir, an antiviral that, like other drugs in its class, is meant to prevent viral replication and cut an illness short. Jamie Ducharme, Time, "The Wuhan Coronavirus Is Spreading Fast. Will Doctors Be Able to Find a Treatment Before the Outbreak Ends?," 22 Jan. 2020 The new treatment is aimed at blocking the enzyme needed for replication. Helena Oliviero, ajc, "GoFundMe for potential coronavirus treatment," 27 Feb. 2020 Those most likely to be sugary, Bertozzi and her colleagues found, are small RNAs known as Y RNAs, which don’t code for proteins, but appear to play a part in DNA replication. Robert F. Service, Science | AAAS, "Sugar-coated RNAs could ‘alter the face of biochemistry as we know it’—if they’re real," 2 Oct. 2019 And while there have been few replication analyses, those that were done have provided valuable insights and suggestions for improving data sharing efforts. Joseph S. Ross, Joanne Waldstreicher, STAT, "Sharing clinical trial data: lessons from the YODA Project," 18 Nov. 2019 If a mad scientist got hold of a turkey and peacock, merged the two, then slapped on some eagle wings, perhaps there would be a chance of replication. Matt Wyatt,, "Pheasant paradise in Kansas," 2 Jan. 2020 Viruses steal a cell’s nucleotides to make more copies of itself, using a special enzyme as their engine of self-replication. Megan Molteni, WIRED, "The Meat-Allergy Tick Also Carries a Mystery Killer Virus," 8 July 2019 Existing therapies often use a small molecule that interferes with viral replication—but this approach does not work for newly emerging viruses or ones that are evolving rapidly. Tanya Lewis, Scientific American, "Scientists Program CRISPR to Fight Viruses in Human Cells," 23 Oct. 2019

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'replication.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of replication

14th century, in the meaning defined at sense 1a

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Time Traveler for replication

Time Traveler

The first known use of replication was in the 14th century

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Statistics for replication

Last Updated

17 Mar 2020

Cite this Entry

“Replication.” Dictionary, Merriam-Webster, Accessed 29 Mar. 2020.

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More Definitions for replication


rep·​li·​ca·​tion | \ ˌrep-lə-ˈkā-shən How to pronounce replication (audio) \

Medical Definition of replication

1 : the action or process of reproducing or duplicating replication of DNA
2 : performance of an experiment or procedure more than once


rep·​li·​ca·​tion | \ ˌre-plə-ˈkā-shən How to pronounce replication (audio) \

Legal Definition of replication

History and Etymology for replication

Anglo-French, from Middle French, from Late Latin replicatio, from Latin, action of folding back, from replicare to fold back

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