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Options include topical or oral minoxidil, antihormonal therapies such as spironolactone (for women), or 5-alpha reductase inhibitors such as finasteride or dutasteride.—Tom Gavin, EverydayHealth.com, 17 Feb. 2026 Urinary nitrite is derived from the metabolism of dietary nitrates (leafy green vegetables) in the presence of bacteria, such as E. coli, which possess the enzyme nitrate reductase.—Neil Gaffin, STAT, 29 Dec. 2025 Sold under the brand names Proscar and Propecia among others, finasteride works by blocking the enzyme 5α-reductase, which changes testosterone into dihydrotestosterone (DHT), the hormone that causes AGA hair follicles to shrink.—Pranjal Malewar, New Atlas, 18 Oct. 2025 An enzyme called 5-alpha reductase changes the hormone into dihydrotestosterone.—Rj MacKenzie, Popular Science, 20 Mar. 2025 Summary Simvastatin and atorvastatin are cholesterol-lowering medications classified as HMG-CoA reductase inhibitors.—Phuoc Anh (anne) Nguyen, Pharmd, Ms, Verywell Health, 18 Dec. 2024 The enzyme that has eluded us for so long is now known as bilirubin reductase.—Elizabeth Rayne, Ars Technica, 27 Jan. 2024