1
: one that is formed first : prototype
2
: a plant cell that has had its cell wall removed
also : the nucleus, cytoplasm, and plasma membrane of a cell as distinguished from inert walls and inclusions

Examples of protoplast in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The cells that star in the team’s wall-building video were protoplasts of Arabidopsis, a small flowering plant belonging to the same family as cabbage and mustard. — ArsTechnica, 4 Apr. 2025 Once the setup was ready, the team fired it up and left the protoplasts in there for 24 hours. — ArsTechnica, 4 Apr. 2025 Moisturize with Shiseido Waso Clear Mega-Hydrating Cream, made with whole carrot protoplasts (what's left of the cell when its wall dissolves). — Maya McDowell, Seventeen, 21 May 2019

Word History

Etymology

Middle French protoplaste, from Late Latin protoplastus first human, from Greek prōtoplastos first formed, from prōt- prot- + plastos formed, from plassein to mold — more at plaster

First Known Use

1532, in the meaning defined at sense 1

Time Traveler
The first known use of protoplast was in 1532

Browse Nearby Words

Cite this Entry

“Protoplast.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/protoplast. Accessed 27 Sep. 2026.

Medical Definition

protoplast

noun
: the nucleus, cytoplasm, and plasma membrane of a cell as distinguished from inert walls and inclusions

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