fi·​bro·​blast | \ˈfī-brə-ˌblast, ˈfi-\

Definition of fibroblast 

: a connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms

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Other Words from fibroblast

fibroblastic \ˌfī-​brə-​ˈbla-​stik, ˌfi-​ \ adjective

Examples of fibroblast in a Sentence

Recent Examples on the Web

Topical retinoids ramp up collagen production in fibroblasts. Allure, "The Skin-Care Glossary: A Comprehensive Guide to Everything You Need to Know," 17 Aug. 2018 Histogen produces its stem cells from skin cells called fibroblasts. Bradley J. Fikes,, "Hair regrowth treatment now being tested in women by La Jolla's Histogen," 12 July 2018 Novoheart’s scientists placed millions of heart cells genetically reprogrammed from stem cells into a mold along with some secret sauce: a dose of dermal fibroblasts, the cells that help your skin repair itself. Megan Molteni, WIRED, "These Beating Mini-Hearts Could Save Big Bucks—And Maybe Lives," 27 June 2018 The crux of the treatment is a fluid containing EGF or epidermal growth factor (FDA-approved), obtained from the progenitor cells of human fibroblasts from Korean newborn baby foreskin. Kathleen Hou, The Cut, "I Tried The ‘Penis Facial’," 16 May 2018 With just a small amount of skin cells called fibroblasts, scientists can grow these so-called induced pluripotent stem cells, then direct them to form human brain tissue. Bradley J. Fikes,, "Salk researchers build better mini-brains to study neurological diseases," 25 Apr. 2018 Using methods that start with tissue cells called fibroblasts, researchers can engineer stem cells, which are cells capable of becoming any kind of body cell. Stephanie Pappas, Scientific American, "Northern White Rhinos Are About to Die Out. Should We Save Them?," 13 Mar. 2018 For years, researchers suspected that tattoos worked by permanently staining fibroblasts, the cells that synthesize collagen, under the surface of our skin. Steph Yin, New York Times, "The Cells That Eat, Regurgitate and Eat Your Tattoos Again," 6 Mar. 2018 The antibodies also make matters worse by attaching to receptors on the macrophages, which in response spit out transforming growth factor β, an immune messenger that activates collagen-producing fibroblasts, leading to fibrosis of tissues. Jon Cohen, Science | AAAS, "A stem cell transplant helped beat back a young doctor’s cancer. Now, it’s assaulting his body," 12 July 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'fibroblast.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of fibroblast

1876, in the meaning defined above

History and Etymology for fibroblast

International Scientific Vocabulary

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15 Dec 2018

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Time Traveler for fibroblast

The first known use of fibroblast was in 1876

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More Definitions for fibroblast


fi·​bro·​blast | \ˈfīb-rə-ˌblast also ˈfib-\

Medical Definition of fibroblast 

: a connective-tissue cell of mesenchymal origin that secretes proteins and especially molecular collagen from which the extracellular fibrillar matrix of connective tissue forms

Other Words from fibroblast

fibroblastic \ˌfīb-​rə-​ˈblas-​tik, ˌfib-​ \ adjective

More from Merriam-Webster on fibroblast

Nglish: Translation of fibroblast for Spanish Speakers Encyclopedia article about fibroblast

Comments on fibroblast

What made you want to look up fibroblast? Please tell us where you read or heard it (including the quote, if possible).


to make faulty or ineffective

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