proinsulin

noun
pro·in·su·lin | \(ˌ)prō-ˈin(t)-s(ə-)lən \

Definition of proinsulin 

: a single-chain pancreatic polypeptide precursor of insulin that gives rise to the double chain of insulin by cleavage and loss of the middle part of the molecule

Examples of proinsulin in a Sentence

Recent Examples on the Web

At Cardiff University and King’s College London, researchers led by Dr. Mohammad Alhadj Ali isolated a compound called a proinsulin C19 A3 peptide. Melissa Healy, The Seattle Times, "Study finds immunotherapy may prevent Type 1 diabetes," 9 Aug. 2017 At Cardiff University and King’s College London, researchers led by Dr. Mohammad Alhadj Ali isolated a compound called a proinsulin C19 A3 peptide. Melissa Healy, latimes.com, "Immunotherapy succeeds in thwarting Type-1 diabetes in study," 9 Aug. 2017 In the 1950s, insulin was derived from the pancreases of cows and pigs and was thought to be contaminated with another protein, which today is known as proinsulin. Denise Gellene, New York Times, "Oliver Smithies, Tinkerer Who Transformed Genetics and Won a Nobel, Dies at 91," 11 Jan. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'proinsulin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of proinsulin

1916, in the meaning defined above

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The first known use of proinsulin was in 1916

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More Definitions for proinsulin

proinsulin

noun
pro·in·su·lin | \(ˈ)prō-ˈin(t)-s(ə-)lən \

Medical Definition of proinsulin 

: a single-chain pancreatic polypeptide precursor of insulin that gives rise to the double chain of insulin by loss of the middle part of the molecule

More from Merriam-Webster on proinsulin

Britannica.com: Encyclopedia article about proinsulin

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