progestin

noun

pro·​ges·​tin prō-ˈje-stən 

: a synthetic progestogen (such as levonorgestrel)

Examples of progestin in a Sentence

Recent Examples on the Web

In addition, higher protein levels in the blood were a stronger predictor of dementia risk in women who took hormone therapy for menopause combining both estrogen and progestin than in women who didn’t use hormones. —Emily Kay Votruba, EverydayHealth.com, 10 Mar. 2026

The study also found that p-tau217 was a stronger predictor of dementia in women who were randomly assigned to receive estrogen and progestin hormone therapy compared to those who received a placebo. —Melissa Rudy, FOXNews.com, 10 Mar. 2026

Hormone replacement therapy − estrogen often coupled with progestin − is the preferred treatment for menopause, according to The Menopause Society. —Laura Trujillo, USA Today, 3 Feb. 2026

Pharmaceutical companies laid low for a while, then added progestin to counter estrogen’s cancer-causing effects and launched a new promotional campaign. —Patricia Bencivenga, STAT, 8 Jan. 2026

Word History

Etymology

progest(ational) + -in entry 1, originally as a name for progesterone

Note: The name was introduced by the American gynecologist and biochemist Willard M. Allen (1904-93) in "Physiology of the Corpus Luteum V. The Preparation and Some Chemical Properties of Progestin, a Hormone of the Corpus Luteum which Produces Progestational Proliferation," Amerian Journal of Physiology, vol. 92, issue 1 (February, 1930), pp. 174-88.

First Known Use

1945, in the meaning defined above

Rhymes for progestin

• clandestine
• intestine

Medical Definition

progestin

noun

pro·​ges·​tin prō-ˈjest-ən 

: a synthetic progestogen (such as levonorgestrel)