prion protein

noun

Definition of prion protein

  1. :  a glycoprotein found especially on the cell surface of neurons in the brain and spinal cord that sometimes occurs in an abnormal misfolded form which proliferates by inducing the normal protein to convert to the misfolded pathogenic form When the normal prion protein misfolds, it resists recycling and forms a hardy gunk. Some aspect of this process produces lethal sponge-like holes in brain cells. — Sandra Blakeslee —abbreviation PrP — see 2prion

1982

First Known Use of prion protein

1982


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to cast off or become cast off

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