pre·fron·tal
(ˌ)prē-ˈfrən-tᵊl 
: anterior to or involving the anterior part of a frontal structure
a prefrontal bone
: a prefrontal part (such as a bone)
Examples of prefrontal in a Sentence
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Mack Degeurin, Popular Science, 15 Jan. 2025
This could profoundly affect the future of humanity within just a few generations by weakening the human prefrontal lobe—the very region that grants us our unique cognitive superiority over all other species.
—Dr. Adil Dalal, Forbes, 14 Jan. 2025
Christie Wilcox, Discover Magazine, 27 June 2018
Dehaene and Changeux postulated that the workspace is instantiated by a network of pyramidal (excitatory) neurons linked to far-flung cortical regions, in particular the prefrontal, parietotemporal and midline (cingulate) associative areas.
—Christof Koch, Scientific American, 1 Dec. 2019
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Adjective
Siracusa says this may be because animals lack a very sophisticated prefrontal cortical function necessary for long-term planning.
—Mack Degeurin, Popular Science, 15 Jan. 2025
This could profoundly affect the future of humanity within just a few generations by weakening the human prefrontal lobe—the very region that grants us our unique cognitive superiority over all other species.
—Dr. Adil Dalal, Forbes, 14 Jan. 2025
Noun
When corrected to brain size, the domesticated rabbits' amygdala's were roughly 9-10% smaller, while their medial prefrontal cortices were about 11-12% bigger.
—Christie Wilcox, Discover Magazine, 27 June 2018
Dehaene and Changeux postulated that the workspace is instantiated by a network of pyramidal (excitatory) neurons linked to far-flung cortical regions, in particular the prefrontal, parietotemporal and midline (cingulate) associative areas.
—Christof Koch, Scientific American, 1 Dec. 2019
See All Example Sentences for prefrontal
Cite this Entry
“Prefrontal.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prefrontal. Accessed 3 Jul. 2025.
Copy CitationMedical Definition
prefrontal
adjective
pre·fron·tal
ˌprē-ˈfrənt-ᵊl
1
: situated or occurring anterior to a frontal structure
a prefrontal bone
2
: of, relating to, or constituting the prefrontal lobe or prefrontal cortex of the brain
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