pre·​clin·​i·​cal | \ (ˌ)prē-ˈkli-ni-kəl How to pronounce preclinical (audio) \

Definition of preclinical

1 : of, relating to, or concerned with the period preceding clinical manifestations
2 : of, relating to, or being the period in medical or dental education preceding the clinical study of medicine or dentistry
3 : occurring prior to clinical testing a preclinical animal study of a new therapy

Examples of preclinical in a Sentence

Recent Examples on the Web

Yes, said Mendell, based on preclinical work, but proof will only come from longer follow-up in the patients to determine if muscle function remains stable or even improves. Adam Feuerstein, STAT, "With tantalizing early results, Sarepta’s gene therapy for Duchenne raises hopes for ‘real change’," 19 June 2018 If preclinical testing keeps going well, the researchers hope to move to clinical trials within five years, Kulkarni said. Martin Finucane,, "Brigham and Women’s researchers take another step toward using immune system to fight cancer," 2 July 2018 Hensley, who also contributed to the preclinical testing of the VSV vaccine, acknowledged her excitement comes with a side of nerves. Helen Branswell, STAT, "‘You’re holding your breath’: Scientists who toiled for years on an Ebola vaccine see the first one put to the test," 22 May 2018 The condition happens in five different stages, starting with what’s known as preclinical Alzheimer’s disease. Korin Miller, SELF, "Are There Early Signs of Alzheimer’s Disease to Watch For?," 28 Nov. 2018 This first stage is called preclinical Alzheimer’s disease, according to the Mayo Clinic. Korin Miller, SELF, "10 Facts About Alzheimer's Disease You Should Know," 28 Sep. 2018 Bender is working to show how his strategy for inhibiting the protein is having success in preclinical trials of mice with multiple sclerosis. Rebecca Lurye,, "Two Yale Researchers Win Blavatnik Grants For The Second Time," 12 May 2018 That day, panel members heard presentations on the drug's preclinical and clinical data from agency staff and AstraZeneca in Cambridge, U.K., its maker and one of the world's largest pharmaceutical companies. Charles Piller, Science | AAAS, "Hidden conflicts? Pharma payments to FDA advisers after drug approvals spark ethical concerns," 5 July 2018 In preclinical coursework, medical students learn in detail about obesity, diabetes, and the immense role diet plays in health and disease. Suhas Gondi, STAT, "Med schools need to get with the times on medical marijuana, chronic pain, and more," 24 Apr. 2018

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'preclinical.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of preclinical

1876, in the meaning defined at sense 1

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1 Mar 2019

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The first known use of preclinical was in 1876

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pre·​clin·​i·​cal | \ (ˈ)prē-ˈklin-i-kəl How to pronounce preclinical (audio) \

Medical Definition of preclinical

1a : of, relating to, concerned with, or being the period preceding clinical manifestations the preclinical stage of diabetes mellitus
b : occurring prior to a clinical trial preclinical animal testing to assess a drug's safety
2 : of, relating to, or being the period in medical or dental education preceding the clinical study of medicine or dentistry the preclinical years specifically : of or relating to the early period of prescribed medical or dental study devoted to the basic sciences (as anatomy, physiology, and pathology) preclinical studies
3 : of, relating to, or being a science basic to medicine research in the preclinical sciences

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