pre·​clin·​i·​cal | \ (ˌ)prē-ˈkli-ni-kəl How to pronounce preclinical (audio) \

Definition of preclinical

1 : of, relating to, or concerned with the period preceding clinical manifestations
2 : of, relating to, or being the period in medical or dental education preceding the clinical study of medicine or dentistry
3 : occurring prior to clinical testing a preclinical animal study of a new therapy

Examples of preclinical in a Sentence

Recent Examples on the Web Armed with cultures and information from Fenical and Jensen, the scientists at Nereus put salinosporamide A through its preclinical paces. Stephanie Stone, Smithsonian Magazine, 2 Sep. 2021 Olson’s research has led to the founding of Delix Therapeutics, which is advancing TBG through preclinical and clinical development. Rebecca Coffey, Forbes, 23 June 2021 Today, drug development in the United States involves a preclinical stage with no human subjects, followed by three phases with progressively more volunteer subjects. Brian Gordon, USA TODAY, 18 Dec. 2020 Ocean Biomedical, a preclinical biotech company founded by Brown University’s Dean of Medicine Dr. Jack Elias and his colleague Dr. Jake Kurtis, is getting ready to go public., 2 Aug. 2021 This raises the possibility of eventually creating diagnostics to catch preclinical melanoma in humans. Maddie Bender, Scientific American, 24 June 2021 The new preclinical drug candidate was found efficacious and safe in mice studies, the company said in a press release. Aayushi Pratap, Forbes, 22 June 2021 This uncertainty hasn’t stopped many drug companies from embarking on at least preclinical research, says Porges. Fortune, 16 Apr. 2021 More than $10 million in donations will help establish the new NYU Langone Center for Psychedelic Medicine, where researchers will continue their work on psychedelics with a focus on psychiatry, medicine, and preclinical research. Amanda Siebert, Forbes, 25 Feb. 2021

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'preclinical.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of preclinical

1876, in the meaning defined at sense 1

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The first known use of preclinical was in 1876

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Last Updated

9 Sep 2021

Cite this Entry

“Preclinical.” Dictionary, Merriam-Webster, Accessed 27 Sep. 2021.

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pre·​clin·​i·​cal | \ (ˈ)prē-ˈklin-i-kəl How to pronounce preclinical (audio) \

Medical Definition of preclinical

1a : of, relating to, concerned with, or being the period preceding clinical manifestations the preclinical stage of diabetes mellitus
b : occurring prior to a clinical trial preclinical animal testing to assess a drug's safety
2 : of, relating to, or being the period in medical or dental education preceding the clinical study of medicine or dentistry the preclinical years specifically : of or relating to the early period of prescribed medical or dental study devoted to the basic sciences (as anatomy, physiology, and pathology) preclinical studies
3 : of, relating to, or being a science basic to medicine research in the preclinical sciences


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