: any of a genus (Cynomys) of gregarious burrowing rodents of the squirrel family chiefly of central and western U.S. plains
especially: a black-tailed rodent (C. ludovicianus) that usually lives in extensive colonial burrows
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These are specialized cartridges intended for shooting small, non-game animals that are essentially pests, including prairie dogs, ground squirrels, coyotes, foxes and rabbits, that are either a threat to agriculture or wildlife management, or are potentially dangerous.—David Szondy
april 19, New Atlas, 19 Apr. 2026 Gambian giant rats and other rodents infected prairie dogs, which in turn infected nearly 100 people who handled the animals.—Jonathan Lambert, NPR, 9 Apr. 2026 The Eastern Colorado prairie was once carpeted with a mix of hardy grasses, flowering plants, and small shrubs that supported great herds of bison and pronghorn, abundant prairie dog colonies, predators like coyotes, foxes, and badgers, as well as numerous bird species, reptiles, and insects.—Krista Kafer, Denver Post, 7 Apr. 2026 Bison roam freely, wild horses graze on ridges, and entire prairie dog towns pop up along the roadside.—Karthika Gupta, Travel + Leisure, 11 Mar. 2026 See All Example Sentences for prairie dog
: a black-tailed buff or grayish rodent of central and western U.S. prairies that is related to the squirrels and usually lives in colonies with many burrows