plu·​rip·​o·​tent | \ plu̇-ˈri-pə-tənt How to pronounce pluripotent (audio) \

Definition of pluripotent

: not fixed as to developmental potentialities especially : capable of differentiating into one of many cell types pluripotent stem cells

Examples of pluripotent in a Sentence

Recent Examples on the Web

Some researchers, including those in Zambidis' lab at Johns Hopkins, are already using one potential alternative: induced pluripotent stem cells, or iPS cells. NBC News, "What is fetal tissue research? And why is it important to medicine?," 9 June 2019 In October 2012, Sir John Gurdon and Shinya Yamanaka were awarded the Nobel Prize for Physiology or Medicine for discovering how to make pluripotent stem cells. Kevin Flower, CNN, "FDA wins major victory in campaign against stem cell clinic," 4 June 2019 Another approach would take advantage of recent breakthroughs in manipulating a kind of stem cell called induced pluripotent stem cells, which can be generated from other adult cells. Daniel Fernandez, Smithsonian, "Can the Northern White Rhino Be Brought Back From the Brink of Extinction?," 22 May 2018 These induced pluripotent stem cells, as they are called, are to be created from the patients themselves. Bradley J. Fikes,, "Rhino pregnancy stirs hope for a nearly extinct species," 17 May 2018 And at Harvard, stem cell biologist Paola Arlotta (also one of the essay's authors) grew 31 human brain organoids over periods as long as nine months and watched as pluripotent stem cells gave rise to human retinal cells alongside other brain cells. Melissa Healy,, "Brainstorming the ethics of neuroscience research in the age of organoids," 27 Apr. 2018 With just a small amount of skin cells called fibroblasts, scientists can grow these so-called induced pluripotent stem cells, then direct them to form human brain tissue. Bradley J. Fikes,, "Salk researchers build better mini-brains to study neurological diseases," 25 Apr. 2018 Theoretically, this can be done by turning frozen rhino cells into cells that can transform into any cell of the body, called pluripotent stem cells. Alessandra Potenza, The Verge, "Inside the high-tech plot to save the northern white rhino from extinction," 6 Apr. 2018 The usual method for making these cells, called induced pluripotent stem (IPS) cells, is to reprogram them by inserting four genes carried by viruses. Bradley J. Fikes,, "Antibody-created stem cells may have superior properties," 11 Sep. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'pluripotent.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of pluripotent

1916, in the meaning defined above

History and Etymology for pluripotent

Latin plur-, plus more + English potent

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18 Jun 2019

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The first known use of pluripotent was in 1916

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plu·​rip·​o·​tent | \ plu̇-ˈrip-ət-ənt How to pronounce pluripotent (audio) \

Medical Definition of pluripotent

1 : not fixed as to developmental potentialities especially : capable of differentiating into one of many cell types pluripotent stem cells
2 : capable of having more than one effect pluripotent activity

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to take the place or position of

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