per·​phe·​na·​zine (ˌ)pər-ˈfē-nə-ˌzēn How to pronounce perphenazine (audio)
: a phenothiazine tranquilizer C21H26ClN3OS that is used especially to control psychotic symptoms (such as anxiety and agitation)

Examples of perphenazine in a Sentence

Recent Examples on the Web First-generation antipsychotics include chlorpromazine, haloperidol, perphenazine, and fluphenazine, the NIMH says. Korin Miller, SELF, 30 Nov. 2018

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'perphenazine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


blend of piperazine and phen-

First Known Use

1957, in the meaning defined above

Time Traveler
The first known use of perphenazine was in 1957

Dictionary Entries Near perphenazine

Cite this Entry

“Perphenazine.” Dictionary, Merriam-Webster, Accessed 21 Jul. 2024.

Medical Definition


per·​phen·​a·​zine (ˌ)pər-ˈfen-ə-ˌzēn How to pronounce perphenazine (audio)
: a phenothiazine tranquilizer C21H26ClN3OS used especially to control symptoms (as anxiety, agitation, and delusions) of psychotic conditions
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