peptidase

noun

pep·​ti·​dase ˈpep-tə-ˌdās How to pronounce peptidase (audio)
-ˌdāz
: an enzyme that hydrolyzes simple peptides or their derivatives

Examples of peptidase in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Lipase breaks down fats, amylase breaks down carbs, and proteases and peptidases both break down proteins, to name a few. Caroline Tien, SELF, 11 Mar. 2026

Word History

First Known Use

1918, in the meaning defined above

Time Traveler
The first known use of peptidase was in 1918

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Cite this Entry

“Peptidase.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/peptidase. Accessed 16 Mar. 2026.

Kids Definition

peptidase

noun
pep·​ti·​dase ˈpep-tə-ˌdās How to pronounce peptidase (audio)
-ˌdāz
: an enzyme that breaks down simple peptides

Medical Definition

peptidase

noun
pep·​ti·​dase ˈpep-tə-ˌdās, -ˌdāz How to pronounce peptidase (audio)
: an enzyme that hydrolyzes simple peptides or their derivatives compare protease

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