pathophysiology

noun

path·​o·​phys·​i·​ol·​o·​gy ˌpa-thō-ˌfi-zē-ˈä-lə-jē How to pronounce pathophysiology (audio)
: the physiology of abnormal states
specifically : the functional changes that accompany a particular syndrome or disease
pathophysiological adjective
or pathophysiologic

Examples of pathophysiology in a Sentence

Recent Examples on the Web The insensitivity to insulin is how type two diabetics lose control of their ability to regulate their blood glucose level and leads to the development and pathophysiology of diabetes. Amber Smith, Discover Magazine, 21 Sep. 2023 This extraordinary improvement in longevity is a testament to our advancements in the treatment and management of HIV, from discoveries and developments in anti-retroviral drugs, treatments for opportunistic infections, and insights into the pathophysiology of this fascinating virus. Rebecca Kreston, Discover Magazine, 25 Nov. 2015 Long-term, mandated innovation education needs to be integrated into medical schools and residencies the same way pathophysiology, medical ethics, and other core knowledge is required today. Marc Succi, STAT, 24 May 2022 The company’s drug, elamipretide, had shown an ability to normalize the synthesis of cardiolipin, a substance mitochondria need to operate correctly and generate energy for the body, thus directly addressing the underlying pathophysiology in this disease. Emily Milligan, STAT, 16 Sep. 2021 In conclusion, our data suggest the hypothalamus to be the primary generator of migraine attacks which, due to specific interactions with specific areas in the higher and lower brainstem, could alter the activity levels of the key regions of migraine pathophysiology. Neuroskeptic, Discover Magazine, 22 May 2016 The quantitative alteration of these cytokines (and others in the same cascade) could help explain in part the complex pathophysiology of Behçet's disease and suggest new therapeutic avenues. Razib Khan, Discover Magazine, 26 July 2010 As long as enough mystery enshrouds the exact pathophysiology of preeclampsia, prevention and therapeutics will fall short. Jessica Winter, The New Yorker, 12 Aug. 2022 The program curriculum is 93 credit hours, which includes core graduate nursing courses, advanced physiology and pathophysiology, chemistry, physics, pharmacology, health assessment and principles of anesthesiology. Megan Becka, cleveland, 18 July 2022

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'pathophysiology.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

probably borrowed from German Pathophysiologie, from patho- patho- + Physiologie physiology

First Known Use

1925, in the meaning defined above

Time Traveler
The first known use of pathophysiology was in 1925

Dictionary Entries Near pathophysiology

Cite this Entry

“Pathophysiology.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/pathophysiology. Accessed 24 Apr. 2024.

Medical Definition

pathophysiology

noun
patho·​phys·​i·​ol·​o·​gy -ˌfiz-ē-ˈäl-ə-jē How to pronounce pathophysiology (audio)
plural pathophysiologies
: the physiology of abnormal states
specifically : the functional changes that accompany a particular syndrome or disease
pathophysiological adjective
or pathophysiologic
pathophysiologist noun

More from Merriam-Webster on pathophysiology

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