pathological

adjective

path·​o·​log·​i·​cal ˌpa-thə-ˈlä-ji-kəl 

variants or less commonly pathologic

ˌpa-thə-ˈlä-jik 

1

: of or relating to pathology

pathological research

A pathological examination led to the diagnosis.

2

: altered or caused by disease

pathological changes in the body

also : indicative of disease

pathological symptoms

3

: being such to a degree that is extreme, excessive, or markedly abnormal

a pathological liar

pathological fear

pathologically

ˌpa-thə-ˈlä-ji-k(ə-)lē 

adverb

Examples of pathological in a Sentence

He is a pathological liar.

She has a pathological fear of heights.

pathological changes in the body

Recent Examples on the Web

In this case, the researchers suggest that the abnormal theta-alpha coupling may reflect a pathological neural signature of OCD. —New Atlas, 3 Aug. 2025

If the amyloid diagnosis is confirmed, patients can be prescribed one of two monoclonal antibodies, both FDA-approved in 2023, that can slow disease progression by targeting and removing pathological amyloid deposits in the brain. —Juergen Eckhardt, Forbes.com, 22 July 2025

Our nation is arguably helped when Newsom’s most unbelievable and pathological tendencies are on full public display. —Will O’Neill, Oc Register, 18 July 2025

Dermatologists typically cite factors such as genetics, UV damage, and underlying pathological conditions. —Andrew Paul, Popular Science, 23 July 2025

Word History

Etymology

New Latin pathologicus "of the study of the passions, of the study of diseases" (borrowed from Greek pathologikós, from patho- patho- + -logikos, from -logia -logy + -ikos -ic entry 1) + -al entry 1

First Known Use

1656, in the meaning defined at sense 1

Rhymes for pathological

• analogical
• astrological
• biological
• christological
• chronological
• cosmological
• cytological
• dialogical
• ecological
• ethnological
• ethological
• geological

Kids Definition

pathological

adjective

patho·​log·​i·​cal

ˌpath-ə-ˈläj-i-kəl

variants also pathologic

-ik

1

: of or relating to pathology

2

: changed or caused by disease

3

: being such to a degree that is extreme, excessive, or abnormal

a pathological liar

pathologically

-i-k(ə-)lē

adverb

Medical Definition

pathological

adjective

patho·​log·​i·​cal ˌpath-ə-ˈläj-i-kəl 

variants also pathologic

-ik 

1

: of or relating to pathology

a pathological laboratory

2

: altered or caused by disease

pathological tissue

also : indicative of disease

pathological lesions

pathologically

-i-k(ə-)lē 

adverb