painkiller

noun

pain·​kill·​er ˈpān-ˌki-lər How to pronounce painkiller (audio)
variants or less commonly pain-killer
Synonyms of painkillernext
: something (such as a drug) that relieves pain
pain-killing adjective
or painkilling

Examples of painkiller in a Sentence

I took some over-the-counter painkillers for my headache. after her oral surgery, she was given a prescription for a mild painkiller
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Cathy believes that Daveigh's addiction began when she was prescribed oxycodone and other painkillers after injuring her back in a motorcycle accident around 2016. Wesley Stenzel, Entertainment Weekly, 20 June 2026 The painkiller marked the beginning of a yearslong descent through addiction — from prescription opioids to methamphetamine, then heroin, and finally, fentanyl. Jonathan Moens — Bellingcat, STAT, 18 June 2026 In recent days, young Knicks fans have been made to digest from their dreary Boomer elders heavy doses of old-timey hoops lore, but mainly about the 1970 title series, featuring Willis Reed’s limping, yet noble appearance in Game Seven, his injured leg shot up with painkillers. David Remnick, New Yorker, 14 June 2026 The first is a multibillion-dollar request to build a next-generation production facility for consumer health products, such as over-the-counter painkillers. Rita McGrath, Harvard Business Review, 4 June 2026 See All Example Sentences for painkiller

Word History

First Known Use

1849, in the meaning defined above

Time Traveler
The first known use of painkiller was in 1849

Browse Nearby Words

Cite this Entry

“Painkiller.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/painkiller. Accessed 26 Jun. 2026.

Kids Definition

painkiller

noun
pain·​kill·​er ˈpān-ˌkil-ər How to pronounce painkiller (audio)
: something (as a drug) that relieves pain
painkilling adjective

Medical Definition

painkiller

noun
pain·​kill·​er -ˌkil-ər How to pronounce painkiller (audio)
: something (as a drug) that relieves pain
painkilling adjective

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