painkiller

noun

pain·​kill·​er ˈpān-ˌki-lər How to pronounce painkiller (audio)
variants or less commonly pain-killer
Synonyms of painkillernext
: something (such as a drug) that relieves pain
pain-killing adjective
or painkilling

Examples of painkiller in a Sentence

I took some over-the-counter painkillers for my headache. after her oral surgery, she was given a prescription for a mild painkiller
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Eric Richins had Lyme disease and was addicted to painkillers, Nester said. CBS News, 23 Feb. 2026 Very few people in pain are going to decline a painkiller, no matter what the cost. Dp Opinion, Denver Post, 21 Feb. 2026 The couple has faced challenges throughout their relationship, including Dane going into rehab in 2011 for an addiction to painkillers after a sports injury. Taylor Ardrey, USA Today, 20 Feb. 2026 Long-term use of over-the-counter painkillers can lead to kidney damage or stomach ulcers. Aria Bendix, NBC news, 20 Feb. 2026 See All Example Sentences for painkiller

Word History

First Known Use

1849, in the meaning defined above

Time Traveler
The first known use of painkiller was in 1849

Browse Nearby Words

Cite this Entry

“Painkiller.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/painkiller. Accessed 25 Feb. 2026.

Kids Definition

painkiller

noun
pain·​kill·​er ˈpān-ˌkil-ər How to pronounce painkiller (audio)
: something (as a drug) that relieves pain
painkilling adjective

Medical Definition

painkiller

noun
pain·​kill·​er -ˌkil-ər How to pronounce painkiller (audio)
: something (as a drug) that relieves pain
painkilling adjective

More from Merriam-Webster on painkiller

Last Updated: - Updated example sentences
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