painkiller

noun

pain·​kill·​er ˈpān-ˌki-lər How to pronounce painkiller (audio)
variants or less commonly pain-killer
Synonyms of painkillernext
: something (such as a drug) that relieves pain
pain-killing adjective
or painkilling

Examples of painkiller in a Sentence

I took some over-the-counter painkillers for my headache. after her oral surgery, she was given a prescription for a mild painkiller
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Overdose deaths fell in 45 states Deaths began steadily climbing in the 1990s with overdoses involving opioid painkillers, followed by waves of deaths from heroin and — more recently — illicit fentanyl. Mike Stobbe, Los Angeles Times, 19 Jan. 2026 Using the common painkiller acetaminophen during pregnancy is not linked to neurodevelopmental disorders in children, according to a study published in the Lancet. Bloomberg News, Boston Herald, 17 Jan. 2026 Acetaminophen is a critical tool for physicians, the go-to drug to use during pregnancy because other commonly available painkillers, such as Advil (ibuprofen), and opioid medications can put a fetus at risk of kidney damage, preterm birth, or even stillbirth. O. Rose Broderick, STAT, 16 Jan. 2026 The color of the sort of deep bruising normally associated with OSHA violations, Chicago’s uniforms herald long periods of bed rest and a night table groaning from the weight of so many prescription painkillers. Anthony Crupi, Sportico.com, 16 Jan. 2026 See All Example Sentences for painkiller

Word History

First Known Use

1849, in the meaning defined above

Time Traveler
The first known use of painkiller was in 1849

Browse Nearby Words

Cite this Entry

“Painkiller.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/painkiller. Accessed 25 Jan. 2026.

Kids Definition

painkiller

noun
pain·​kill·​er ˈpān-ˌkil-ər How to pronounce painkiller (audio)
: something (as a drug) that relieves pain
painkilling adjective

Medical Definition

painkiller

noun
pain·​kill·​er -ˌkil-ər How to pronounce painkiller (audio)
: something (as a drug) that relieves pain
painkilling adjective

More from Merriam-Webster on painkiller

Last Updated: - Updated example sentences
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