oncogene

noun
on·​co·​gene | \ ˈäŋ-kō-ˌjēn How to pronounce oncogene (audio) \

Definition of oncogene

: a gene having the potential to cause a normal cell to become cancerous

Examples of oncogene in a Sentence

Recent Examples on the Web In the case of cancer, this means some cells wind up with more oncogenes than the others. San Diego Union-Tribune, "San Diego startup raises nearly $47 million for new approach to fighting cancer," 19 Sep. 2019 The cancer genes, called oncogenes, were not malignant in themselves, Dr. Leder and his research team concluded. Matt Schudel, Washington Post, "Philip Leder, medical researcher who explored genetic links to cancer, dies at 85," 15 Feb. 2020 Daughter cells with more copies of these oncogenes grow faster, as do their descendants, Mischel said. San Diego Union-Tribune, "San Diego startup raises nearly $47 million for new approach to fighting cancer," 19 Sep. 2019 The drug targets overexpressed estrogen receptors that can be predicted by the Her-2/Neu oncogene, which was discovered more than a decade earlier. Scientific American, "The Coming Age of Molecular Medicine," 2 Oct. 2019 This allows mutated cancer-promoting genes called oncogenes to activate cell surface receptors, molecular portals to the cell’s interior. San Diego Union-Tribune, "Biotech notebook: Cancer discovery, bacterial syringes and organoids," 13 July 2019 This drug, eFT226, blocks translation of certain oncogenes, including MYC, BCL2, cyclin D1 and CDKs 4/6. Bradley J. Fikes, sandiegouniontribune.com, "San Diego cancer biotech raises $38.6 million," 24 July 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'oncogene.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of oncogene

1969, in the meaning defined above

History and Etymology for oncogene

onco- + gene

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Time Traveler for oncogene

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The first known use of oncogene was in 1969

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Last Updated

11 May 2020

Cite this Entry

“Oncogene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/oncogene. Accessed 7 Jun. 2020.

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More Definitions for oncogene

oncogene

noun
on·​co·​gene | \ ˈäŋ-kō-ˌjēn How to pronounce oncogene (audio) \

Medical Definition of oncogene

: a gene having the potential to cause a normal cell to become cancerous

More from Merriam-Webster on oncogene

Britannica English: Translation of oncogene for Arabic Speakers

Britannica.com: Encyclopedia article about oncogene

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