oncogene

noun

on·​co·​gene ˈäŋ-kō-ˌjēn How to pronounce oncogene (audio)
: a gene having the potential to cause a normal cell to become cancerous

Examples of oncogene in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Additionally, cancer cells with many copies of the MYCN oncogene on ecDNA grow quickly but are more easily destroyed by chemotherapy. Noah Lyons, San Diego Union-Tribune, 26 Aug. 2025 Viruses that actually do cause cancer are characterized by direct integration into the genetic structure of the host, the development of viral oncogenes or chronic infection (think Hepatitis B, for example) that can tragically result in liver cancer. Armstrong Williams, Baltimore Sun, 2 Aug. 2025 It's hoped the novel drug will be able to stunt the growth and enable the effective treatment of cancers driven by the MYC oncogene and its MYC protein. Bronwyn Thompson, New Atlas, 13 June 2025 When these genes mutate, they are then called oncogenes. Lindsay Curtis, Health, 14 Feb. 2025 Traditional treatments use mutation location To attempt to answer this question, our research team chose to focus on one oncogene in lung cancer, EGFR, or epidermal growth factor receptor. Jacqulyne Robichaux, The Conversation, 25 Oct. 2021 At first scientists thought TP53 was an oncogene, meaning that mutations within it would cause cancer. Anna Funk, Discover Magazine, 17 May 2021

Word History

Etymology

onco- + gene

First Known Use

1969, in the meaning defined above

Time Traveler
The first known use of oncogene was in 1969

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Cite this Entry

“Oncogene.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/oncogene. Accessed 9 Sep. 2025.

Kids Definition

oncogene

noun
on·​co·​gene ˈäŋ-kō-ˌjēn How to pronounce oncogene (audio)
: a gene having the potential to cause a normal cell to become cancerous

Medical Definition

oncogene

noun
on·​co·​gene ˈäŋ-kō-ˌjēn How to pronounce oncogene (audio)
: a gene having the potential to cause a normal cell to become cancerous

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