nortriptyline

noun

nor·​trip·​ty·​line nȯr-ˈtrip-tə-ˌlēn 

: a tricyclic antidepressant C₁₉H₂₁N used in the form of its hydrochloride

Examples of nortriptyline in a Sentence

Recent Examples on the Web

While SSRIs affect only the neurotransmitter serotonin, tricyclic antidepressants such as amitriptyline and nortriptyline impact both serotonin and norepinephrine and other chemical messengers. — Kristen Rogers, CNN Money, 14 May 2026

For example, a person who took nortriptyline, a tricyclic antidepressant, could, on average, have an increase in heart rate that was 20 beats higher than the SSRI fluvoxamine. — Will Stone, NPR, 23 Oct. 2025

Word History

Etymology

nor- + -tript- (perhaps from tricyclic + hepta-) + -yl + -ine entry 2

First Known Use

1962, in the meaning defined above

Rhymes for nortriptyline

• amitriptyline

Medical Definition

nortriptyline

noun

nor·​trip·​ty·​line nȯr-ˈtrip-tə-ˌlēn 

: a tricyclic antidepressant administered in the form of its hydrochloride C₁₉H₂₁N·HCl see aventyl