nortriptyline

noun

nor·​trip·​ty·​line nȯr-ˈtrip-tə-ˌlēn How to pronounce nortriptyline (audio)
: a tricyclic antidepressant C19H21N used in the form of its hydrochloride

Examples of nortriptyline in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
For example, a person who took nortriptyline, a tricyclic antidepressant, could, on average, have an increase in heart rate that was 20 beats higher than the SSRI fluvoxamine. Will Stone, NPR, 23 Oct. 2025

Word History

Etymology

nor- + -tript- (perhaps from tricyclic + hepta-) + -yl + -ine entry 2

First Known Use

1962, in the meaning defined above

Time Traveler
The first known use of nortriptyline was in 1962

Browse Nearby Words

Cite this Entry

“Nortriptyline.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nortriptyline. Accessed 29 Jan. 2026.

Medical Definition

nortriptyline

noun
nor·​trip·​ty·​line nȯr-ˈtrip-tə-ˌlēn How to pronounce nortriptyline (audio)
: a tricyclic antidepressant administered in the form of its hydrochloride C19H21N·HCl see aventyl

More from Merriam-Webster on nortriptyline

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!