nortriptyline
noun
nor·trip·ty·line
nȯr-ˈtrip-tə-ˌlēn 
: a tricyclic antidepressant C19H21N used in the form of its hydrochloride
Examples of nortriptyline in a Sentence
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While SSRIs affect only the neurotransmitter serotonin, tricyclic antidepressants such as amitriptyline and nortriptyline impact both serotonin and norepinephrine and other chemical messengers.
—
Kristen Rogers, CNN Money, 14 May 2026
For example, a person who took nortriptyline, a tricyclic antidepressant, could, on average, have an increase in heart rate that was 20 beats higher than the SSRI fluvoxamine.
—Will Stone, NPR, 23 Oct. 2025
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Kristen Rogers, CNN Money, 14 May 2026
For example, a person who took nortriptyline, a tricyclic antidepressant, could, on average, have an increase in heart rate that was 20 beats higher than the SSRI fluvoxamine.
—Will Stone, NPR, 23 Oct. 2025
Cite this Entry
“Nortriptyline.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nortriptyline. Accessed 19 May. 2026.
Copy CitationMedical Definition
nortriptyline
noun
nor·trip·ty·line
nȯr-ˈtrip-tə-ˌlēn
: a tricyclic antidepressant administered in the form of its hydrochloride C19H21N·HCl see aventyl
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