nocebo effect

noun

: the development of adverse side effects or worsening in the condition of a patient that occurs in response to medical treatment but cannot be considered due to the specific treatment used
With a nocebo effect, if test subjects believe there may be side effects, they often experience them. Again, expectations shape reality.Sanjay Gupta

Examples of nocebo effect in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
That’s the nocebo effect—the evil twin of the placebo. David Meade, Forbes.com, 18 July 2025 The nocebo effect is another important aspect of mindset. Jennifer C. Lovejoy, Scientific American, 7 Dec. 2022 Marino, who watched the video, told the San Diego Union-Tribune a nocebo effect could explain Faiivae's reaction since his symptoms did not suggest an overdose. Miriam Fauzia, USA TODAY, 25 Aug. 2021 The placebo effect also has a shadowy twin: the nocebo effect. Carl Engelking, Discover Magazine, 5 Oct. 2017

Word History

First Known Use

1969, in the meaning defined above

Time Traveler
The first known use of nocebo effect was in 1969

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Cite this Entry

“Nocebo effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nocebo%20effect. Accessed 8 Sep. 2025.

Medical Definition

nocebo effect

noun
: the development of adverse side effects or worsening in the condition of a patient that occurs in response to medical treatment but cannot be considered due to the specific treatment used
With a nocebo effect, if test subjects believe there may be side effects, they often experience them. Again, expectations shape reality.Sanjay Gupta, Chasing Life: New Discoveries In The Search For Immortality …
The placebo effect has an evil twin: the nocebo effect, in which dummy pills and negative expectations can produce harmful effects.Helen Pilcher, New Scientist
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