neoadjuvant

adjective

neo·​ad·​ju·​vant ˌnē-ō-ˈa-jə-vənt How to pronounce neoadjuvant (audio)
medical
: of, relating to, or being treatment (such as chemotherapy or hormone therapy) administered before primary cancer treatment (such as surgery) to enhance the outcome of primary treatment
In certain breast cancer, neoadjuvant therapies reduce recurrences by 50 percent in some situations.Jen Waters
The use of preoperative (neoadjuvant) chemotherapy before resection of the primary pulmonary tumor is controversial, and data are lacking to guide clinicians.Michael Lanuti et al.
compare adjuvant entry 1 sense 2

Examples of neoadjuvant in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The study, published in Nutrition and Cancer and newly making headlines this week, followed 80 women over 45 receiving neoadjuvant chemotherapy at Botucatu School of Medicine, São Paulo State University. Allison Palmer, Sacbee.com, 30 Apr. 2026 The randomized clinical trial, published in Nutrition and Cancer and newly making headlines this week, followed 80 women over 45 undergoing neoadjuvant chemotherapy at Botucatu School of Medicine in Brazil. Allison Palmer, Miami Herald, 30 Apr. 2026 The randomized clinical trial, published in Nutrition and Cancer and newly making waves this week, followed 80 women over age 45 receiving neoadjuvant chemotherapy at São Paulo State University in Brazil. Allison Palmer, Kansas City Star, 30 Apr. 2026 This strategy could be a promising neoadjuvant therapy prior to checkpoint blockades or other cancer therapies. Jasmine Laws, MSNBC Newsweek, 24 July 2025 In addition to different surgical techniques, neoadjuvant chemotherapy or immunotherapy is now being used more often. Marla Anderson, Verywell Health, 8 July 2025 Once that initial treatment—known as neoadjuvant or pre-operative treatment—is done, surgery is then performed for people healthy enough to undergo it. Sayaka Blickenderfer, Phd, Health, 18 Sep. 2024 First would be eight rounds of neoadjuvant chemotherapy over about four months, before surgical extraction of the tumor. Paige Stables, Allure, 22 Nov. 2023

Word History

Etymology

neo- + adjuvant entry 2

First Known Use

1984, in the meaning defined above

Time Traveler
The first known use of neoadjuvant was in 1984

Browse Nearby Words

Cite this Entry

“Neoadjuvant.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/neoadjuvant. Accessed 16 May. 2026.

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

More from Merriam-Webster