naltrexone

noun

nal·​trex·​one nal-ˈtrek-ˌsōn 

: a synthetic opiate antagonist C₂₀H₂₃NO₄ administered in the form of its hydrochloride

Examples of naltrexone in a Sentence

Recent Examples on the Web

Based on its influence on immune and neurochemical pathways, for example, low-dose naltrexone is under investigation as a potential therapy for certain inflammatory and autoimmune diseases, including multiple sclerosis and Crohn disease. —Encyclopedia Britannica, 26 Mar. 2026

Some medications, like naltrexone and buprenorphine, are used specifically to prevent relapse in people trying to recover from opioid use disorder. —Jon Hamilton, NPR, 10 Mar. 2026

This is more than double the 14% reduction that the same study found with naltrexone, which was the best-performing medication approved for treatment of alcohol use disorder in that analysis. —Ziyad Al-Aly, Fortune, 5 Mar. 2026

This is more than double the 14% reduction that the same study found with naltrexone, which was the best-performing medication approved for treatment of alcohol use disorder in that analysis. —Ziyad Al-Aly, The Conversation, 4 Mar. 2026

Word History

Etymology

N-allyl + trex- (as in methotrexate) + -one

First Known Use

1973, in the meaning defined above

Medical Definition

naltrexone

noun

nal·​trex·​one nal-ˈtrek-ˌsōn 

: a synthetic opiate antagonist administered especially in the form of its hydrochloride C₂₀H₂₃NO₄·HCl to maintain a drug-free state in detoxified opiate-dependent patients or to maintain abstinence in alcohol-dependent patients