multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor

Examples of multiple sclerosis in a Sentence

Recent Examples on the Web

Had multiple sclerosis finally come for me after all this time? —Michelle Maves, MSNBC Newsweek, 18 Oct. 2025

Treg cells also control internal revolt in the form of an overactive immune response by other immune cells that can trigger allergies and autoimmune diseases such as arthritis, lupus and multiple sclerosis – diseases that develop when Treg cells are defective in either number, function or both. —Mitzi Nagarkatti, The Conversation, 10 Oct. 2025

This discovery provides a foundation for understanding and treating autoimmune diseases such as type 1 diabetes and multiple sclerosis. —Sujita Sinha, Interesting Engineering, 7 Oct. 2025

Autoimmune diseases such as lupus, rheumatoid arthritis and multiple sclerosis are a spectrum of diseases that affect patients of all ages, oftentimes with devastating or even fatal effects, said Daniel Kastner, a distinguished investigator at the National Institutes of Health. —Katie Hunt, CNN Money, 6 Oct. 2025

Word History

First Known Use

1885, in the meaning defined above

Rhymes for multiple sclerosis

• actinomycosis
• atherosclerosis
• endometriosis
• erythematosus
• erythroblastosis
• granulomatosis
• hemochromatosis
• histiocytosis
• hyperkeratosis
• ketoacidosis
• mononucleosis
• osteonecrosis

Kids Definition

multiple sclerosis

noun

: a disease marked by patches of hardened tissue in the brain or spinal cord resulting in symptoms (as weakness or paralysis in the arms or legs or loss of balance and muscle coordination) that usually come and go

Medical Definition

multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor