multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor

Examples of multiple sclerosis in a Sentence

Recent Examples on the Web

Similarly, Sanofi’s tolebrutinib for non-relapsing secondary progressive multiple sclerosis, and Aldeyra Therapeutics’ reproxalap for ocular disease have each generated substantial concern among patients, clinicians, sponsors, or advocates. — Jeffrey Sonnenfeld, Fortune, 14 July 2026

Las Vegas Raiders quarterback Fernando Mendoza wants to help make a difference for people who, like his mom, are living with multiple sclerosis, or MS, a chronic condition that attacks and damages the body’s nervous system. — Michelle Marchante, Miami Herald, 10 July 2026

Jeffreys noted that multiple sclerosis can fluctuate, with some patients able to work full time, some able to work flexibly and others unable to work at all. — Michelle Mbekeani, Forbes.com, 1 July 2026

Harvard Health reports the associations may stretch well beyond the gut, from autoimmune diseases like lupus, type 1 diabetes and multiple sclerosis to chronic fatigue, fibromyalgia, arthritis, allergies, asthma, acne, obesity and even mental illness. — Ryan Brennan, Sacbee.com, 24 June 2026

Word History

First Known Use

1885, in the meaning defined above

Rhymes for multiple sclerosis

• actinomycosis
• atherosclerosis
• endometriosis
• erythematosus
• erythroblastosis
• granulomatosis
• hemochromatosis
• histiocytosis
• hyperkeratosis
• ketoacidosis
• mononucleosis
• osteonecrosis

Kids Definition

multiple sclerosis

noun

: a disease marked by patches of hardened tissue in the brain or spinal cord resulting in symptoms (as weakness or paralysis in the arms or legs or loss of balance and muscle coordination) that usually come and go

Medical Definition

multiple sclerosis

noun

: a demyelinating disease marked by patches of hardened tissue in the brain or the spinal cord and associated especially with partial or complete paralysis and jerking muscle tremor