mule

1 of 3

noun (1)

ˈmyül 

1

a

: a hybrid between a horse and a donkey

especially : the offspring of a male donkey and a mare

b

: a self-sterile plant whether hybrid or not

c

: a usually sterile hybrid

2

: a very stubborn person

3

: a machine for simultaneously drawing and twisting fiber into yarn or thread and winding it into cops

4

slang : a person who smuggles or delivers illicit substances (such as drugs)

mule

2 of 3

noun (2)

: a shoe or slipper without quarter or heel strap compare scuff

mule

3 of 3

noun (3)

variants or less commonly Mule

plural mules also Mules

: moscow mule

Mules are traditionally lime, vodka, and ginger beer served in a copper mug, a very refreshing beverage …

—Santino Mattioli

The marvelous take on a classic mule swaps ginger beer for ginger kombucha … for a crisp, fresh-tasting award-worthy cocktail …

—PR Newswire

Examples of mule in a Sentence

Recent Examples on the Web

Noun

In the first onscreen interaction between them, Rue, now working as a drug mule for a dealer named Laurie (Martha Kelly), wends her way through a labyrinthine house party before meeting Alamo, sitting in a hot tub, flanked by four strippers, and wearing a Speedo and a cowboy hat. —Molly Lambert, Vulture, 20 Apr. 2026

The most obvious influence right from the Season 3 opening, in which drug mule Rue (Zendaya) struggles to make her way across the border, is the American Western, a reference point that greatly excited production designer François Audouy. —Jim Hemphill, IndieWire, 19 Apr. 2026

There were 80 people out searching for Sites as of Saturday morning, including more drone teams and mules, the sheriff’s office said. —Katie Langford, Denver Post, 18 Apr. 2026

The mules have a short, 8-millimeter heel that has extra padding for maximum support and comes in four neutral shades. —Rachel Trujillo, PEOPLE, 13 Apr. 2026

Word History

Etymology

Noun (1)

Middle English, from Anglo-French mul, from Latin mulus

Noun (2)

Middle French, a kind of slipper, from Latin mulleus shoe worn by magistrates

Noun (3)

short for moscow mule

First Known Use

Noun (1)

13th century, in the meaning defined at sense 1a

Noun (2)

1562, in the meaning defined above

Noun (3)

1996, in the meaning defined above

Phrases Containing mule

• (as) stubborn as a mule
• Moscow mule
• mule deer
• mule skinner

Rhymes for mule

• boule
• brule
• buhl
• cool
• drool
• fool
• ghoul
• pool
• poul
• rule
• school
• spool

Kids Definition

mule

1 of 2 noun

ˈmyü(ə)l 

1

: the hybrid offspring of a horse and a donkey

especially : the offspring of a male donkey and a female horse

2

: a very stubborn person

3

: a machine that draws and twists fiber into yarn or thread and winds it onto spindles

mule

2 of 2 noun

: a shoe or slipper that is open at the heel

Etymology

Noun

Middle English mule "the offspring of a donkey and a horse," from early French mul (same meaning), from Latin multus (same meaning)

Noun

from early French mule "slipper," from mulleus "a shoe worn by public officials"

Medical Definition

mule

noun

ˈmyü(ə)l 

: a hybrid between a horse and a donkey

especially : the offspring of a male donkey and a mare