mono·​gen·​ic | \ ˌmä-nə-ˈje-nik How to pronounce monogenic (audio) \

Definition of monogenic

: of, relating to, or controlled by a single gene and especially by either of an allelic pair

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Other Words from monogenic

monogenically \ ˌmä-​nə-​ˈje-​ni-​k(ə-​)lē How to pronounce monogenic (audio) \ adverb

Examples of monogenic in a Sentence

Recent Examples on the Web Not surprisingly, those advocating for preimplantation genetic testing prefer to keep the conversation focused on monogenic diseases, where single gene mutations have severe health effects. Sarah Zhang, The Atlantic, 18 Nov. 2020 Even for the most well-researched, monogenic diseases, such as cystic fibrosis, there are vast gaps in our knowledge. John Stuelpnagel, Fortune, 13 Jan. 2020 But even if 23andMe wanted to, the SNP technology doesn't allow it, since many of the 1,400 monogenic conditions are diagnosed using techniques other than SNP testing. Thomas Goetz, WIRED, 17 Nov. 2007

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'monogenic.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of monogenic

1939, in the meaning defined above

History and Etymology for monogenic

International Scientific Vocabulary

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Time Traveler for monogenic

Time Traveler

The first known use of monogenic was in 1939

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Cite this Entry

“Monogenic.” Dictionary, Merriam-Webster, Accessed 2 Aug. 2021.

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More Definitions for monogenic


mono·​gen·​ic | \ -ˈjen-ik How to pronounce monogenic (audio) , -ˈjēn- How to pronounce monogenic (audio) \

Medical Definition of monogenic

: of, relating to, or controlled by a single gene and especially by either of an allelic pair

Other Words from monogenic

monogenically \ -​i-​k(ə-​)lē How to pronounce monogenic (audio) \ adverb


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