monogenic

adjective

mono·​gen·​ic ˌmä-nə-ˈje-nik How to pronounce monogenic (audio)
: of, relating to, or controlled by a single gene and especially by either of an allelic pair
monogenically adverb

Examples of monogenic in a Sentence

Recent Examples on the Web The goal is to turn PASTE into a medicine for rare, monogenic disease and use the technology to craft cell therapies for more common ailments. Damian Garde, STAT, 12 Dec. 2023 Much of his line of attack against modern genetics which displeases him is to construct a strawman of monogenic models, when the reality is that polygenic variation is widely acknowledged and understood, within the academy! Razib Khan, Discover Magazine, 20 Nov. 2012 Not surprisingly, those advocating for preimplantation genetic testing prefer to keep the conversation focused on monogenic diseases, where single gene mutations have severe health effects. Sarah Zhang, The Atlantic, 18 Nov. 2020 Even for the most well-researched, monogenic diseases, such as cystic fibrosis, there are vast gaps in our knowledge. John Stuelpnagel, Fortune, 13 Jan. 2020 But even if 23andMe wanted to, the SNP technology doesn't allow it, since many of the 1,400 monogenic conditions are diagnosed using techniques other than SNP testing. Thomas Goetz, WIRED, 17 Nov. 2007

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'monogenic.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

International Scientific Vocabulary

First Known Use

1939, in the meaning defined above

Time Traveler
The first known use of monogenic was in 1939

Dictionary Entries Near monogenic

Cite this Entry

“Monogenic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/monogenic. Accessed 1 Mar. 2024.

Medical Definition

monogenic

adjective
mono·​gen·​ic -ˈjen-ik How to pronounce monogenic (audio) -ˈjēn- How to pronounce monogenic (audio)
: of, relating to, or controlled by a single gene and especially by either of an allelic pair
monogenically adverb
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