monkeypox

noun

mon·​key·​pox ˈməŋ-kē-ˌpäks How to pronounce monkeypox (audio)
: mpox

Note: This disease was first identified in monkeys in 1958, although the natural reservoir (see reservoir sense 3a) has not been identified. The virus has been found in various animals including rodents and primates.

Note: As of 2022, the World Health Organization (WHO) uses the name mpox to refer to this disease due to the stigmatizing nature of the original name.

Examples of monkeypox in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In 2022, Florida was part of a nationwide outbreak of monkeypox. Cindy Krischer Goodman, Sun Sentinel, 27 May 2025 Trump’s attacks on the civil service have stripped the government of the experienced public officials needed to manage public health responses; cuts to USAID, for example, have frozen its work in Africa to contain Marburg virus, monkeypox, and other diseases with pandemic potential. Edward Alden, Foreign Affairs, 6 Mar. 2025 The first human case of monkeypox was recorded in the Democratic Republic of Congo in 1970. Kizzy Cox, Essence, 16 Aug. 2024 And the stock prices of two pharmaceutical giants rose after the World Health Organization declared monkeypox a public health emergency. Laura Bratton, Quartz, 16 Aug. 2024 See All Example Sentences for monkeypox

Word History

First Known Use

1960, in the meaning defined above

Time Traveler
The first known use of monkeypox was in 1960

Browse Nearby Words

Cite this Entry

“Monkeypox.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/monkeypox. Accessed 9 Nov. 2025.

Medical Definition

monkeypox

noun
mon·​key·​pox ˈməŋ-kē-ˌpäks How to pronounce monkeypox (audio)
: mpox

Note: As of 2022, the World Health Organization (WHO) uses the name mpox to refer to this disease due to the stigmatizing nature of the original name.

More from Merriam-Webster on monkeypox

Last Updated: - Definition revised
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!