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mis·sus | \ ˈmi-səz 
, -səs, especially Southern -zəz \
, -səs, especially Southern -zəz \variants:
or missis
Definition of missus
1 informal + old-fashioned : wife … everybody knew Mr. Levov and everybody asked after the missus and the boys.— Philip Roth
2 British, informal —used to address a woman whose name is not known
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Time Traveler for missus
The first known use of missus was in 1790
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