methylprednisolone

noun

meth·​yl·​pred·​nis·​o·​lone ˌme-thəl-pred-ˈni-sə-ˌlōn How to pronounce methylprednisolone (audio)
: a glucocorticoid C22H30O5 that is a derivative of prednisolone and is used as an anti-inflammatory agent
also : any of several of its salts (such as an acetate) used similarly

Examples of methylprednisolone in a Sentence

Recent Examples on the Web
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This includes budesonide, a steroid used in treating the inflammatory bowel disease Crohn's disease, and Medrol (methylprednisolone), which treats several inflammatory conditions. Ross Phan, Verywell Health, 9 Feb. 2026 Depending on the case, your provider may order a low-dose steroid like Medrol (methylprednisolone) instead.2 Fabhalta (iptacopan) targets a different immune pathway that causes kidney inflammation. Brandi Jones, Health, 7 Jan. 2026 At least six products are on the FDA’s shortages list, including dexamethasone sodium phosphate and methylprednisolone acetate injections. Meghana Keshavan, STAT, 12 Feb. 2024

Word History

First Known Use

1957, in the meaning defined above

Time Traveler
The first known use of methylprednisolone was in 1957

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Cite this Entry

“Methylprednisolone.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/methylprednisolone. Accessed 24 Apr. 2026.

Medical Definition

methylprednisolone

noun
meth·​yl·​pred·​nis·​o·​lone -pred-ˈnis-ə-ˌlōn How to pronounce methylprednisolone (audio)
: a glucocorticoid C22H30O5 that is a derivative of prednisolone and is used as an anti-inflammatory agent
also : any of several of its salts (as an acetate) used similarly see medrol
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