meth·​a·​done | \ ˈme-thə-ˌdōn How to pronounce methadone (audio) \
variants: or less commonly methadon \ ˈme-​thə-​ˌdän How to pronounce methadone (audio) \

Definition of methadone

: a synthetic addictive narcotic drug C21H27NO used especially in the form of its hydrochloride for the relief of pain and as a substitute narcotic in the treatment of heroin addiction

Examples of methadone in a Sentence

Recent Examples on the Web Currently, people seeking help with addiction can take medications like naltrexone, methadone and buprenorphine: These often life-changing medications prevent cravings, feelings of being high or both. Tribune News Service, oregonlive, 6 Jan. 2022 Felix Barela received 78 months for dealing heroin, cocaine and methadone; others went away for two years for distributing less than 100 grams (about 3.5 ounces) of heroin. Alicia Inez Guzmán, Rolling Stone, 30 Nov. 2021 In addition to methadone, drug policy experts say every doctor should be allowed to prescribe buprenorphine, another life-saving drug for opioid use disorder that has been shown to greatly reduce the risk of fatal overdose. Zachary Siegel, The New Republic, 24 Nov. 2021 Unlike methadone, buprenorphine is available by prescription. Sarah Fielding,, 17 Nov. 2021 Typically, this medically assisted treatment is through medications such as methadone — synthetic narcotics administered in a way to decrease reliance and help patients through addiction treatment. IndyStar, 20 Dec. 2021 Two others, including a woman arrested on her way into a methadone clinic, were released on their own recognizance., 6 Nov. 2021 Some other reasons for false positives on a home pregnancy test can include protein or blood present in urine and certain types of prescription drugs like methadone, anticonvulsants (to treat seizures) and medications for anxiety. Miriam Fauzia, USA TODAY, 27 Sep. 2021 For treating individuals with opioid use disorder, for instance, that means a combination of medications like buprenorphine or methadone, along with psychosocial support. Kirsi Goldynia, CNN, 19 Nov. 2021

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'methadone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of methadone

1947, in the meaning defined above

History and Etymology for methadone

methyl + amino + diphenyl + -one

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Time Traveler for methadone

Time Traveler

The first known use of methadone was in 1947

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Dictionary Entries Near methadone

methacrylic acid



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Statistics for methadone

Last Updated

9 Jan 2022

Cite this Entry

“Methadone.” Dictionary, Merriam-Webster, Accessed 28 Jan. 2022.

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More Definitions for methadone



English Language Learners Definition of methadone

: a drug that people take to help them stop taking heroin


meth·​a·​done | \ ˈmeth-ə-ˌdōn How to pronounce methadone (audio) \
variants: also methadon \ -​ˌdän How to pronounce methadone (audio) \

Medical Definition of methadone

: a synthetic addictive narcotic drug used especially in the form of its hydrochloride C21H27NO·HCl for the relief of pain and as a substitute narcotic in the treatment of heroin addiction

called also amidone

More from Merriam-Webster on methadone

Nglish: Translation of methadone for Spanish Speakers Encyclopedia article about methadone


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