meth·​a·​done | \ ˈme-thə-ˌdōn How to pronounce methadone (audio) \
variants: or less commonly methadon \ ˈme-​thə-​ˌdän How to pronounce methadone (audio) \

Definition of methadone

: a synthetic addictive narcotic drug C21H27NO used especially in the form of its hydrochloride for the relief of pain and as a substitute narcotic in the treatment of heroin addiction

Examples of methadone in a Sentence

Recent Examples on the Web Heroin is a Schedule I drug while morphine, fentanyl, oxycodone (Percocet) and methadone are Schedule II. Cnn Editorial Research, CNN, "Opioid Crisis Fast Facts," 14 Apr. 2021 Harm reduction is typically thought of in the context of formalized programs – methadone clinics and syringe service programs – but experts say the way Lovato speaks about her own moderation could fall under the umbrella of harm reduction. Alia E. Dastagir, USA TODAY, "Demi Lovato has alcohol, weed in moderation: What experts think of the 'California Sober' approach," 6 Apr. 2021 Longtime developer Frank Keefe helped lead that project for the university, and remembers bringing investors to look at the south side of Commonwealth Avenue, then home to a Supersocks store and a methadone clinic., "For Kenmore Square, does the end of an era mean a promising future?," 3 Apr. 2021 Evidence showed that Heaton had Alprazolam, fentanyl, methadone, and morphine in her system at the time of the wreck. Carol Robinson |, al, "Woman gets 30 years in prison for DUI head-on crash that killed her 3-year-old son and 79-year-old man," 7 Apr. 2021 In October, researchers in Spain began testing ibogaine in 20 people trying to wean themselves off methadone. Mandy Oaklander, Time, "Inside Ibogaine, One of the Most Promising and Perilous Psychedelics for Addiction," 5 Apr. 2021 According to Britannica, she was denied methadone treatment and her body had to detox on its own. Lia Beck,, "The United States Vs. Billie Holiday," 28 Feb. 2021 Christine Finnigan, 53, has been on methadone for two years to treat her opioid use disorder. John Keilman,, "Woman who sued DuPage County sheriff to receive methadone treatment in jail loses court fight but could still get her meds," 25 Feb. 2021 The singer had been given methadone to aid her recovery, but she was cut off after 10 days on Anslinger’s request. Erica Gonzales, Harper's BAZAAR, "The United States vs. Billie Holiday: What Really Happened," 26 Feb. 2021

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'methadone.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

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First Known Use of methadone

1947, in the meaning defined above

History and Etymology for methadone

methyl + amino + diphenyl + -one

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Time Traveler for methadone

Time Traveler

The first known use of methadone was in 1947

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Statistics for methadone

Last Updated

27 Apr 2021

Cite this Entry

“Methadone.” Dictionary, Merriam-Webster, Accessed 7 May. 2021.

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English Language Learners Definition of methadone

: a drug that people take to help them stop taking heroin


meth·​a·​done | \ ˈmeth-ə-ˌdōn How to pronounce methadone (audio) \
variants: also methadon \ -​ˌdän How to pronounce methadone (audio) \

Medical Definition of methadone

: a synthetic addictive narcotic drug used especially in the form of its hydrochloride C21H27NO·HCl for the relief of pain and as a substitute narcotic in the treatment of heroin addiction

called also amidone

More from Merriam-Webster on methadone

Nglish: Translation of methadone for Spanish Speakers Encyclopedia article about methadone

Comments on methadone

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