me·​tas·​ta·​size mə-ˈta-stə-ˌsīz How to pronounce metastasize (audio)
metastasized; metastasizing

intransitive verb

: to spread or grow by or as if by metastasis
died of lung cancer which had metastasized throughout his bodyG. P. Elliott

Examples of metastasize in a Sentence

Recent Examples on the Web Multiple security officials across Europe describe a threat that is metastasizing as Russian agents, increasingly under scrutiny by security services and frustrated in their own operations, hire local amateurs to undertake high-risk, and often deniable, crimes on their behalf. Nick Paton Walsh, CNN, 10 July 2024 Weeks passed; in the absence of arrests, rumors metastasized online. Rachel Monroe, The New Yorker, 21 June 2024 Otherwise, domestic violent extremism will continue to fester and metastasize, putting more lives at risk. Cynthia Miller-Idriss, Foreign Affairs, 8 July 2022 If the tropical disturbance does metastasize into a storm — the National Weather Service estimates that happening later Wednesday — heavy rainfall is certain to inundate parts of South Texas. David Montesino, Fort Worth Star-Telegram, 19 June 2024 See all Example Sentences for metastasize 

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'metastasize.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of metastasize was in 1907

Dictionary Entries Near metastasize

Cite this Entry

“Metastasize.” Dictionary, Merriam-Webster, Accessed 18 Jul. 2024.

Kids Definition


me·​tas·​ta·​size mə-ˈtas-tə-ˌsīz How to pronounce metastasize (audio)
: to spread or grow by or as if by metastasis

Medical Definition


intransitive verb
variants also British metastasise
metastasized also British metastasised; metastasizing also British metastasising
: to spread by metastasis
… all ten were primary brain cancers; that is, they had originated in the brain, and not metastasized there from elsewhere in the body.Paul Brodeur, The New Yorker
metastasization noun
also British metastasisation
Last Updated: - Updated example sentences
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