metastasize

verb

me·​tas·​ta·​size mə-ˈta-stə-ˌsīz How to pronounce metastasize (audio)
metastasized; metastasizing

intransitive verb

: to spread or grow by or as if by metastasis
… died of lung cancer which had metastasized throughout his body.G. P. Elliott

Examples of metastasize in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
From there, the situation metastasized into a crisis for Paramount. Winston Cho, HollywoodReporter, 4 June 2026 Mellencamp announced that the cancer had metastasized in March 2025. Shania Russell, Entertainment Weekly, 3 June 2026 The overall five-year survival rate is just 14 percent, and that number drops even lower if the cancer has spread (metastasized) to other parts of the body. Tom Gavin, EverydayHealth.com, 2 June 2026 These tumors can grow rapidly, invade surrounding blood vessels, and may even metastasize to other organs such as the liver. The Washington Post, San Diego Union-Tribune, 30 May 2026 See All Example Sentences for metastasize

Word History

First Known Use

1907, in the meaning defined above

Time Traveler
The first known use of metastasize was in 1907

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Cite this Entry

“Metastasize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/metastasize. Accessed 5 Jun. 2026.

Kids Definition

metastasize

verb
me·​tas·​ta·​size mə-ˈtas-tə-ˌsīz How to pronounce metastasize (audio)
: to spread or grow by or as if by metastasis

Medical Definition

metastasize

intransitive verb
me·​tas·​ta·​size
variants also British metastasise
metastasized also British metastasised; metastasizing also British metastasising
: to spread by metastasis
… all ten were primary brain cancers; that is, they had originated in the brain, and not metastasized there from elsewhere in the body.Paul Brodeur, The New Yorker
metastasization noun
also British metastasisation
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