1
: transformation of one tissue into another
2
: abnormal replacement of cells of one type by cells of another

Examples of metaplasia in a Sentence

Recent Examples on the Web
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This inflammatory response turns them into columnar cells, resulting in columnar metaplasia. — Mark Gurarie, Health, 7 Mar. 2025 Other theories have included immune dysfunction, chronic inflammation, and metaplasia (an abnormal change in the tissue). — Abby Haglage, SELF, 25 Oct. 2017

Word History

Etymology

New Latin

First Known Use

1883, in the meaning defined at sense 1

Time Traveler
The first known use of metaplasia was in 1883

Browse Nearby Words

Cite this Entry

“Metaplasia.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/metaplasia. Accessed 2 Oct. 2026.

Medical Definition

1
: transformation of one tissue into another
metaplasia of cartilage into bone
2
: abnormal replacement of cells of one type by cells of another

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