1
: staining or characterized by staining in a different color or shade from what is typical
metachromatic granules in a bacterium
2
: having the capacity to stain different elements of a cell or tissue in different colors or shades
metachromatic stains

Examples of metachromatic in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The couple’s children were born with metachromatic leukodystrophy (MLD), which causes muscle weakness, progressive loss of vision and eventual paralysis. — Diane Moca, Chicago Tribune, 3 Sep. 2022 So much has changed for them since the early months of the pandemic, when the couple's middle daughter, Olivia, was diagnosed with a rare genetic disorder called metachromatic leukodystrophyf, or MLD. — Priscilla Totiyapungprasert, The Arizona Republic, 5 Sep. 2020 My daughter Calliope has a terminal illness called metachromatic leukodystrophy. — Maria Kefalas, STAT, 2 Dec. 2019 The four-year-old has a rare disease called metachromatic leukodystrophy that could rob him of the ability to walk, sit and hold up his own head within the next year. — Chicago Tribune Staff, chicagotribune.com, 18 Nov. 2019

Word History

First Known Use

1876, in the meaning defined at sense 1

Time Traveler
The first known use of metachromatic was in 1876

Browse Nearby Words

Cite this Entry

“Metachromatic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/metachromatic. Accessed 4 Oct. 2026.

Medical Definition

metachromatic

adjective
1
: staining or characterized by staining in a different color or shade from what is typical
metachromatic granules
2
: having the capacity to stain different elements of a cell or tissue in different colors or shades
metachromatic stains
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!