Mesoamerican

adjective

Me·​so·​amer·​i·​can ˌme-zō-ə-ˈmer-i-kən 

ˌmē-, 

-sō-

: of, relating to, or characteristic of Mesoamerica (a region extending from modern northwestern Mexico approximately to El Salvador that was occupied during pre-Columbian times) or its peoples (as the Olmecs, Mayans, and Aztecs)

Mesoamerican noun

plural Mesoamericans

Examples of Mesoamerican in a Sentence

Recent Examples on the Web

Known as chronic kidney disease of unknown etiology (CKDu) — or Mesoamerican nephropathy — the condition continues to baffle researchers, as some otherwise healthy adults develop kidney failure without having any of the traditional risk factors. — Shiv Sudhakar, FOXNews.com, 15 Sep. 2026

The musicians, discreetly performing at the back of the stage under the guidance of Mesoamerican instruments director Christopher García, charge the air with percussive Indigenous wonder. — Theater Critic, Los Angeles Times, 11 Sep. 2026

Her massive concrete site-work, which takes up the entirety of the Geffen Galleries plaza, is peppered with fragmentary representations of the Mesoamerican deity Quetzalcoatl and the simulated footprints of Californian fauna. — George Baker, Artforum, 1 Sep. 2026

But many of its adoring fans have little idea of its origins, which reach back thousands of years to pre-Hispanic, Mesoamerican cultures in Mexico. — Alfredo Sosa, Christian Science Monitor, 22 Aug. 2026

Word History

First Known Use

1948, in the meaning defined above

Rhymes for Mesoamerican

• american