mes·​en·​chy·​mal mə-ˈzeŋ-kə-məl How to pronounce mesenchymal (audio)
: of, resembling, or being mesenchyme

Examples of mesenchymal in a Sentence

Recent Examples on the Web Several early-stage clinical trials in the U.S. are exploring the use of mesenchymal stem cells, modified in the lab and injected into the spinal fluid of patients with progressive forms of M.S., in the hope of reversing the disease’s progression. Rivka Galchen, The New Yorker, 17 July 2023 What the study showed In the study of 565 heart failure patients from 52 treatment centers, half were given high doses of these mesenchymal stem cells and the other half a sham procedure. Karen Weintraub, USA TODAY, 28 Feb. 2023 The therapy involves injecting mesenchymal precursor cells into the heart. Jacqueline Howard, CNN, 27 Feb. 2023 Hair dermal papillae cells are specialized mesenchymal cells located in the dermal papilla, where the latter is found at the bottom of hair follicles. Amber Smith, Discover Magazine, 8 Sep. 2021 The research includes projects on stem cells, biologicals, small molecules, mesenchymal stromal cells, extracellular vesicles, microRNAs, peptides, genetic manipulations, other signaling agents and more. WSJ, 10 Jan. 2023 What is your opinion regarding mesenchymal cell injections? Dr. Keith Roach, oregonlive, 18 May 2022 It’s this: In some contexts, cells known as mesenchymal or stromal cells (generally going by the acronym MSCs) have anti-inflammatory and immune suppressing functions. Paul Knoepfler, STAT, 27 June 2021 Exosomes from mesenchymal stem cells are also popular because stem cells tend to avoid immune detection. Amanda B. Keener, Scientific American, 17 June 2020 See More

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'mesenchymal.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History


International Scientific Vocabulary

First Known Use

1883, in the meaning defined above

Time Traveler
The first known use of mesenchymal was in 1883

Dictionary Entries Near mesenchymal

Cite this Entry

“Mesenchymal.” Dictionary, Merriam-Webster, Accessed 2 Dec. 2023.

Medical Definition


mes·​en·​chy·​mal mə-ˈzeŋ-kə-məl How to pronounce mesenchymal (audio) -ˈseŋ-; ˌmez-ᵊn-ˈkī-məl How to pronounce mesenchymal (audio)
: of, resembling, or being mesenchyme
mesenchymal cells
mesenchymal epithelium
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