mediator

noun

me·​di·​a·​tor ˈmē-dē-ˌā-tər How to pronounce mediator (audio)
1
: one that mediates
especially : one that mediates between parties at variance
2
: a mediating agent in a physical, chemical, or biological process

Examples of mediator in a Sentence

if you two cannot resolve this argument on your own, we'll have to bring in a mediator
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Negotiations to secure a 60-day ceasefire between Israel and Hamas seem to have hit an impasse amid hopes from top mediators, including President Donald Trump’s Middle East Special Envoy Steve Witkoff, that a deal can be reached soon. Caitlin McFall, FOXNews.com, 13 July 2025 And that then triggers these cells, called the mast cells, to release all these inflammatory mediators, like histamine and other kinds of mediators, like nutrients, which can have profound effects. Josh Hammer, MSNBC Newsweek, 9 July 2025 Tehran, for its part, was once again open to speaking directly to American officials rather than exclusively through mediators. Mohammad Ayatollahi Tabaar, Foreign Affairs, 8 July 2025 Another way that cortisol can help manage stress in the short term is by suppressing your immune system and the release of different inflammatory mediators. Bruce Y. Lee, Forbes.com, 5 July 2025 See All Example Sentences for mediator

Word History

First Known Use

14th century, in the meaning defined at sense 1

Time Traveler
The first known use of mediator was in the 14th century

Browse Nearby Words

Cite this Entry

“Mediator.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/mediator. Accessed 22 Jul. 2025.

Kids Definition

mediator

noun
me·​di·​a·​tor ˈmēd-ē-ˌāt-ər How to pronounce mediator (audio)
: one that mediates
mediatory
-ē-ə-ˌtōr-ē
-ˌtȯr-
adjective

Medical Definition

mediator

noun
me·​di·​a·​tor ˈmēd-ē-ˌāt-ər How to pronounce mediator (audio)
: one that mediates
especially : a mediating agent (as an enzyme or hormone) in a chemical or biological process
substance P, a neuropeptide mediator of analgesic stimuli in peripheral sensory nerves D. R. Robinson

Legal Definition

mediator

noun
me·​di·​a·​tor ˈmē-dē-ˌā-tər How to pronounce mediator (audio)
: one that works to effect reconciliation, settlement, or compromise between parties at variance compare arbitrator

More from Merriam-Webster on mediator

Last Updated: - Updated example sentences
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