mast cell

noun

: a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (such as histamine and heparin) which mediate allergic reactions

Examples of mast cell in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The meeting further presented the extraordinary evidence that effective treatments for these issues are already available, such as anti-histamines, probiotics, mast cell stabilisers – simple, cheap, low risk medications which have made the difference between someone working and not working. Nancy Doyle, Forbes.com, 15 July 2025 And that then triggers these cells, called the mast cells, to release all these inflammatory mediators, like histamine and other kinds of mediators, like nutrients, which can have profound effects. Josh Hammer, MSNBC Newsweek, 9 July 2025 In 2022, Halsey shared on Instagram that they had been diagnosed with Ehlers-Danlos syndrome, Sjogren’s syndrome, mast cell activation syndrome — known as MCAS — and postural orthostatic tachycardia syndrome, known as POTS. Shania Russell, EW.com, 4 June 2024 Monoclonal antibodies eliminate the signals that trigger mast cells. Kate Raphael, Discover Magazine, 23 June 2025 See All Example Sentences for mast cell

Word History

Etymology

partial translation of German Mastzelle, from Mast food, mast (from Old High German) + Zelle cell

First Known Use

circa 1890, in the meaning defined above

Time Traveler
The first known use of mast cell was circa 1890

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Cite this Entry

“Mast cell.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/mast%20cell. Accessed 20 Aug. 2025.

Medical Definition

mast cell

noun
: a granulocyte that occurs especially in connective tissue and has basophilic granules containing substances (as histamine and heparin) which mediate allergic reactions

More from Merriam-Webster on mast cell

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