lyophilize

1 of 2

verb

ly·​oph·​i·​lize lī-ˈä-fə-ˌlīz How to pronounce lyophilize (audio)
lyophilized; lyophilizing
lyophilization noun
lyophilizer noun

lyophilization

2 of 2

noun

ly·​oph·​i·​li·​za·​tion (ˌ)lī-ˌä-fə-lə-ˈzā-shən How to pronounce lyophilization (audio)
-fə-ˌlī-ˈzā-
variants also British lyophilisation
plural -s
: the process of freeze-drying or the state of being freeze-dried

Word History

Etymology

Noun

International Scientific Vocabulary lyophilize + -ation

First Known Use

Verb

1938, in the meaning defined above

Time Traveler
The first known use of lyophilize was in 1938

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Cite this Entry

“Lyophilize.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/lyophilize. Accessed 25 Jun. 2026.

Medical Definition

lyophilize

transitive verb
ly·​oph·​i·​lize
variants or British lyophilise
lyophilized or British lyophilised; lyophilizing or British lyophilising
lyophilization noun
or British lyophilisation
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