: a lipoprotein of blood plasma that is composed of a moderate proportion of protein with little triglyceride and a high proportion of cholesterol and that is associated with increased probability of developing atherosclerosis : bad cholesterol compare hdl

Examples of LDL in a Sentence

Recent Examples on the Web
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Fiber alone can slow digestion, improve blood sugar control, and help lower LDL cholesterol, all of which can benefit cardiometabolic health. — Lauren Manaker Ms, HEALTH, 18 Sep. 2026 This is noteworthy because high levels of triglycerides and LDL cholesterol can cause arterial blockages, potentially leading to heart disease. — Kirsten Nunez, Martha Stewart, 12 Sep. 2026 Medications available today can already lower LDL cholesterol to the levels found in the study. — Sandee Lamotte, CNN Money, 28 Aug. 2026 The main cholesterol and blood fat names to pay attention to are LDL, HDL, and triglycerides. — Gavin Escott, USA Today, 13 Aug. 2026 See All Example Sentences for LDL

Word History

Etymology

low-density lipoprotein

First Known Use

1962, in the meaning defined above

Time Traveler
The first known use of LDL was in 1962

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Cite this Entry

“LDL.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/LDL. Accessed 30 Sep. 2026.

Medical Definition

: a lipoprotein of blood plasma that is composed of a moderate proportion of protein with little triglyceride and a high proportion of cholesterol and that is associated with increased probability of developing atherosclerosis

called also bad cholesterol, beta-lipoprotein, low-density lipoprotein

compare hdl, vldl
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