: a lipoprotein of blood plasma that is composed of a high proportion of protein with little triglyceride and cholesterol and that is correlated with reduced risk of atherosclerosis : good cholesterol compare ldl

Examples of HDL in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Those who regularly consumed whole grains had increased their high-density lipoprotein (HDL) cholesterol. Cynthia Sass, Health, 5 Nov. 2025 Older beta-blockers and high-dose diuretics may slightly raise LDL cholesterol and lower HDL cholesterol. Jennifer Moll, Verywell Health, 24 Sep. 2025 Omega-3 fatty acids lower blood pressure and inflammation and improve HDL and LDL cholesterol. Chrystle Fiedler, USA Today, 19 Sep. 2025 See All Example Sentences for HDL

Word History

Etymology

high-density lipoprotein

First Known Use

1954, in the meaning defined above

Time Traveler
The first known use of HDL was in 1954

Browse Nearby Words

Cite this Entry

“HDL.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/HDL. Accessed 10 Nov. 2025.

Medical Definition

: a lipoprotein of blood plasma that is composed of a high proportion of protein with little triglyceride and cholesterol and that is associated with decreased probability of developing atherosclerosis

called also alpha-lipoprotein, good cholesterol, high-density lipoprotein

compare ldl, vldl
Last Updated: - Updated example sentences
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!