isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

also ˌi-

: the action of isolating : the condition of being isolated

Synonyms of isolation

• solitude
• privacy
• loneliness

Choose the Right Synonym for isolation

solitude, isolation, seclusion mean the state of one who is alone.

solitude may imply a condition of being apart from all human beings or of being cut off by wish or circumstances from one's usual associates.

a few quiet hours of solitude

isolation stresses detachment from others often involuntarily.

the isolation of the village in winter

seclusion suggests a shutting away or keeping apart from others often connoting deliberate withdrawal from the world or retirement to a quiet life.

lived in pastoral seclusion

Examples of isolation in a Sentence

the isolation of the mountain community

after the long book tour, the author looked forward to the isolation of his office

Recent Examples on the Web

The San José Unified School District, as an example, has incorporated a 40-hour community service requirement throughout high school into its curriculum as part of an effort to encourage engagement with the broader community, foster empathy and reduce social isolation among students. —Muhammad Aquil, San Diego Union-Tribune, 4 June 2026

Meanwhile, at least 11 international activists traveling overland to challenge Israel’s Gaza blockade are being held in Libya on immigration charges, highlighting the widening fallout of the enclave’s isolation. —Wafaa Shurafa, Los Angeles Times, 4 June 2026

Whether your overall financial plan needs adjusting Student loans rarely exist in isolation. —Angelica Leicht, CBS News, 4 June 2026

Academic performance, particularly USMLE scores, provides a standardized reference point, but experienced evaluators read scores in context as opposed to in isolation. —Lyssanoel Frater, USA Today, 3 June 2026

Word History

First Known Use

1833, in the meaning defined above

Phrases Containing isolation

• in isolation
• reproductive isolation
• self-isolation

Rhymes for isolation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

also ˌis-ə-

1

: the act of isolating : the condition of being isolated

2

: separation of a population of living things from related forms in such a manner as to prevent crossbreeding

Medical Definition

isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

1

: the action of isolating or condition of being isolated

isolation of a virus

put the patient in isolation

2

: a segregation of a group of organisms from related forms in such a manner as to prevent crossing

3

: a psychological defense mechanism consisting of the separating of ideas or memories from the emotions connected with them