isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən How to pronounce isolation (audio)
also ˌi-
Synonyms of isolation
: the action of isolating : the condition of being isolated
Choose the Right Synonym for isolation

solitude, isolation, seclusion mean the state of one who is alone.

solitude may imply a condition of being apart from all human beings or of being cut off by wish or circumstances from one's usual associates.

a few quiet hours of solitude

isolation stresses detachment from others often involuntarily.

the isolation of the village in winter

seclusion suggests a shutting away or keeping apart from others often connoting deliberate withdrawal from the world or retirement to a quiet life.

lived in pastoral seclusion

Examples of isolation in a Sentence

the isolation of the mountain community after the long book tour, the author looked forward to the isolation of his office
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Most access points are reached from the west side, coming through Meeker, and Grimes noted that despite the isolation, the gravel roads are well-maintained, meaning a passenger vehicle should get you to most trailheads. Jamie Siebrase, Denver Post, 26 June 2026 Some of the recent statistics on digital isolation and loneliness are startling. Liz Thach, Forbes.com, 25 June 2026 Any individuals who may have had contact with the patient will undergo a 21-day period of home isolation, during which they will be closely monitored by health authorities. Lauren Kent, CNN Money, 24 June 2026 Working in isolation, cut off from the outside world and subjected to extreme conditions, the crew faces an even greater threat when the station’s doctor becomes infected by a highly contagious parasitic worm. Melanie Goodfellow, Deadline, 24 June 2026 See All Example Sentences for isolation

Word History

First Known Use

1833, in the meaning defined above

Time Traveler
The first known use of isolation was in 1833

Cite this Entry

“Isolation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isolation. Accessed 27 Jun. 2026.

Kids Definition

isolation

noun
iso·​la·​tion ˌī-sə-ˈlā-shən How to pronounce isolation (audio)
also ˌis-ə-
1
: the act of isolating : the condition of being isolated
2
: separation of a population of living things from related forms in such a manner as to prevent crossbreeding

Medical Definition

isolation

noun
iso·​la·​tion ˌī-sə-ˈlā-shən How to pronounce isolation (audio)
1
: the action of isolating or condition of being isolated
isolation of a virus
put the patient in isolation
2
: a segregation of a group of organisms from related forms in such a manner as to prevent crossing
3
: a psychological defense mechanism consisting of the separating of ideas or memories from the emotions connected with them

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