isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

also ˌi-

: the action of isolating : the condition of being isolated

Synonyms of isolation

• solitude
• privacy
• loneliness

Choose the Right Synonym for isolation

solitude, isolation, seclusion mean the state of one who is alone.

solitude may imply a condition of being apart from all human beings or of being cut off by wish or circumstances from one's usual associates.

a few quiet hours of solitude

isolation stresses detachment from others often involuntarily.

the isolation of the village in winter

seclusion suggests a shutting away or keeping apart from others often connoting deliberate withdrawal from the world or retirement to a quiet life.

lived in pastoral seclusion

Examples of isolation in a Sentence

the isolation of the mountain community

after the long book tour, the author looked forward to the isolation of his office

Recent Examples on the Web

To play Stallone, Ippolito explored the hardships that shaped — and fueled — the older actor, including a difficult childhood, limited parental support and a profound sense of isolation. — ABC News, 4 Nov. 2026

One major breakthrough involved simplifying the particle isolation process. — Aamir Khollam, Interesting Engineering, 4 Nov. 2026

Given that Dhaka is one of the globe’s most densely populated cities, the world Zaineen inhabits requires a great deal of control to maintain this kind of isolation. — Jay Weissberg, Variety, 3 Nov. 2026

According to Tito’s, 100% of the proceeds of the Turkey Rot lineup through its online store will benefit Meals on Wheels America, which addresses hunger and isolation among senior citizens. — Stacy Lambe, PEOPLE, 2 Nov. 2026

Word History

First Known Use

1833, in the meaning defined above

Phrases Containing isolation

• in isolation
• reproductive isolation
• self-isolation

Rhymes for isolation

• abdication
• aberration
• abjuration
• abnegation
• abrogation
• acceptation
• acclamation
• acclimation
• accusation
• activation
• actuation
• acylation

Kids Definition

isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

also ˌis-ə-

1

: the act of isolating : the condition of being isolated

2

: separation of a population of living things from related forms in such a manner as to prevent crossbreeding

Medical Definition

isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən 

1

: the action of isolating or condition of being isolated

isolation of a virus

put the patient in isolation

2

: a segregation of a group of organisms from related forms in such a manner as to prevent crossing

3

: a psychological defense mechanism consisting of the separating of ideas or memories from the emotions connected with them