isolation

noun

iso·​la·​tion ˌī-sə-ˈlā-shən How to pronounce isolation (audio)
 also  ˌi-
: the action of isolating : the condition of being isolated
Choose the Right Synonym for isolation

solitude, isolation, seclusion mean the state of one who is alone.

solitude may imply a condition of being apart from all human beings or of being cut off by wish or circumstances from one's usual associates.

a few quiet hours of solitude

isolation stresses detachment from others often involuntarily.

the isolation of the village in winter

seclusion suggests a shutting away or keeping apart from others often connoting deliberate withdrawal from the world or retirement to a quiet life.

lived in pastoral seclusion

Examples of isolation in a Sentence

the isolation of the mountain community after the long book tour, the author looked forward to the isolation of his office
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The capital’s development over the past eight years, despite sanctions and the extreme isolation of the Covid-19 pandemic, stunned him. Will Ripley, CNN Money, 30 Oct. 2025 Prolonged isolation simply unleashes Jack from the moral strictures holding him back. Sophie Gilbert, The Atlantic, 30 Oct. 2025 Xuexin Duan, who leads the Tianjin University group, and his colleagues set out to invent a tool that would not only lessen the threat to cells during the isolation process, but speed the whole process up. Perri Thaler, IEEE Spectrum, 30 Oct. 2025 To ward off feelings of isolation, founders and top executives are stepping outside of the office to focus on improving their well-being. Emma Burleigh, Fortune, 29 Oct. 2025 See All Example Sentences for isolation

Word History

First Known Use

1833, in the meaning defined above

Time Traveler
The first known use of isolation was in 1833

Cite this Entry

“Isolation.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/isolation. Accessed 7 Nov. 2025.

Kids Definition

isolation

noun
iso·​la·​tion ˌī-sə-ˈlā-shən How to pronounce isolation (audio)
 also  ˌis-ə-
1
: the act of isolating : the condition of being isolated
2
: separation of a population of living things from related forms in such a manner as to prevent crossbreeding

Medical Definition

isolation

noun
iso·​la·​tion ˌī-sə-ˈlā-shən How to pronounce isolation (audio)
1
: the action of isolating or condition of being isolated
isolation of a virus
put the patient in isolation
2
: a segregation of a group of organisms from related forms in such a manner as to prevent crossing
3
: a psychological defense mechanism consisting of the separating of ideas or memories from the emotions connected with them

More from Merriam-Webster on isolation

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