He suffered an irreversible loss of vision.
The crisis has done irreversible harm to the countries' relations.
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Merriam-Webster defines it as the description of someone or something in a state of possibly irreversible misfortune and hardship.—Brenda Looper, Washington Post, 8 Jan. 2026 This not only triggers power struggles and deep psychological shifts, but there could also be irreversible decisions around control, freedom and dynamics within our society.—Valerie Mesa, PEOPLE, 5 Jan. 2026 Scientists and clinicians reported advances that addressed conditions once thought irreversible, from congenital deafness and rare mitochondrial disorders to cancers that have long resisted treatment.—Kaif Shaikh, Interesting Engineering, 1 Jan. 2026 Dark or Brightly Colored Clothing Lemon juice can have a bit of a bleaching effect on dark and brightly colored clothing and textiles, leading to irreversible color loss.—Jolie Kerr, Better Homes & Gardens, 23 Dec. 2025 See All Example Sentences for irreversible
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