medical Definition of integrin
- Through these 20 or more integrins, the [extracellular] matrix sends cells various signals that regulate what genes are active, ultimately influencing whether cells proliferate, specialize, migrate, or even kill themselves.
- —Richard Monastersky, Science News, 30 Aug. 1997
- Early on we understood that integrins consist of two protein chains, or subunits. The subunit designated “alpha” is today known to have about 15 variants, and the “beta” subunit has about eight variants.
- —Alan F. Horwitz, Scientific American, May 1997
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